Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 8/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.47 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MYOC | Q99972 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7718000 | 0.91 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL542086 | 0.80 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9994168 | 0.80 | MAPT (0.60) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL28879715 | 0.79 | HTR2A (0.47) | ALDH1A1KMT2AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL18684993 | 0.78 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2APOLBLMNA | |
| SCHEMBL542087 | 0.78 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL27889264 | 0.77 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL5583400 | 0.77 | ALDH1A1 (0.56) | ALDH1A1NPC1RAB9APOLBMAPT | |
| SCHEMBL8654472 | 0.76 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL4361293 | 0.76 | ALDH1A1 (0.55) | ALDH1A1NPC1RAB9AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384264-B1 | NITRATION OF AN AROMATIC ALDEHYDE/KETONE TO AN O-NITRO DERIVATIVE AND REDUCING IT TO AN ALCOHOL, REACTING THE ALCOHOL WITH A MONO/DIISOCYANATES TO PROVIDE A 2-NITROBENZYL URETHANE CAPABLE OF GENERATING FREE AMINES UPON IRRADIATION | AGFA-GEVAERT (BE) | 2002-05-07 | — | — | US | disclosed |
| US-6171756-B1 | SOLVENT SOLUBLE ORGANIC PHOTOPRECURSORS OF AMINES FOR USE IN PHOTOSENSITIVE IMAGING SYSTEMS, SAID PHOTOPRECURSORS GENERATING FREE AMINES ON EXPOSURE TO LONG WAVELENGTH UV OR VISIBLE RADIATION, COMPRISING PHOTOLABILE 2-NITROBENZYL GROUPS | AFGA-GEVAERT, N.V. (BE) | 2001-01-09 | — | — | US | disclosed |
| EP-0926555-A1 | Photoactive materials applicable to imaging systems. | AGFA-GEVAERT N.V. (BE) | 1999-06-30 | — | — | EP | disclosed |