Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27889264 | 0.87 | ALDH1A1 (0.56) | ALDH1A1CYP1A2TSHRSMN1; SMN2GAA | |
| SCHEMBL13347474 | 0.86 | ALDH1A1 (0.59) | ALDH1A1CYP1A2TSHRSMN1; SMN2GAA | |
| SCHEMBL5052181 | 0.86 | ALDH1A1 (0.55) | ALDH1A1CYP1A2TSHRSMN1; SMN2GAA | |
| SCHEMBL4361293 | 0.86 | ALDH1A1 (0.55) | ALDH1A1CYP1A2TSHRSMN1; SMN2GAA | |
| SCHEMBL29573208 | 0.86 | ALDH1A1 (0.55) | ALDH1A1CYP1A2TSHRSMN1; SMN2GAA | |
| SCHEMBL27918543 | 0.85 | ALDH1A1 (0.58) | ALDH1A1CYP1A2TSHRSMN1; SMN2GAA | |
| SCHEMBL12050502 | 0.85 | ALDH1A1 (0.58) | ALDH1A1CYP1A2TSHRSMN1; SMN2GAA | |
| SCHEMBL9775501 | 0.85 | ALDH1A1 (0.51) | ALDH1A1CYP1A2TSHRSMN1; SMN2GAA | |
| SCHEMBL12894152 | 0.84 | ALDH1A1 (0.43) | ALDH1A1CYP1A2TSHRSMN1; SMN2GAA | |
| SCHEMBL23072537 | 0.83 | ALDH1A1 (0.52) | ALDH1A1CYP1A2TSHRSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894373-A | N-substituted benzylpyrazole derivatives as beta 2 Use of allosteric modulators, antagonists and agonists of the adrenergic receptor | 常州大学 | 2023-04-04 | — | — | CN | disclosed |
| US-7301049-B2 | Photolabile esters and their uses | THE INSTITUTE OF CANCER RESEARCH (GB) | 2007-11-27 | — | — | US | disclosed |
| US-20070190526-A1 | Methods of extracting nucleic acids | NEXGEN DIAGNOSTICS LLC | 2007-08-16 | — | — | US | disclosed |
| US-20070185322-A1 | Methods of extracting RNA | NEXGEN DIAGNOSTICS LLC | 2007-08-09 | — | — | US | disclosed |
| US-20040242653-A1 | Photolabile esters and their uses | THE INSTITUTE OF CANCER RESEARCH (GB) | 2004-12-02 | — | — | US | disclosed |
| EP-1399412-A1 | PHOTOLABILE ESTERS AND THEIR USES | The Institute of Cancer Research (GB) | 2004-03-24 | — | — | EP | disclosed |
| WO-2003000644-A1 | PHOTOLABILE ESTERS AND THEIR USES | THE INSTITUTE OF CANCER RESEARCH (GB) | 2003-01-03 | — | — | WO | disclosed |
| US-5981146-A | CONTAINING A COMPOUND HAVING A SULFONIC ACID GROUP OR A CARBONIC ACID GROUP IS FORMED ON A CHEMICAL-AMPLIFICATION-TYPE RESIST FILM OF A SEMICONDUCTTOR SUBSTRATE, FOLLOWED BY PERFORMING EXPOSURE | MITSUBISHI DENKI KABUSHIKI KAISHA (JP) | 1999-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070190526-A1 | Methods of extracting nucleic acids | DNASE1, RNASE1, POLRMT | ALDH1A1 4435/4885CYP1A2 4857/4885TSHR 3187/4885 |
| US-20070185322-A1 | Methods of extracting RNA | RNASE1, RNASEH1, DNASE1 | ALDH1A1 4718/4885CYP1A2 4864/4885TSHR 2538/4885 |
| US-20040242653-A1 | Photolabile esters and their uses | DIMT1, DCTD, DTYMK | ALDH1A1 2920/4885CYP1A2 4649/4885TSHR 1938/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.