⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL419299 | 0.72 | TSHR (0.46) | — | |
| SCHEMBL278164 | 0.72 | — | — | |
| SCHEMBL24397619 | 0.71 | TSHR (0.40) | — | |
| SCHEMBL18844904 | 0.71 | TSHR (0.40) | — | |
| SCHEMBL1176918 | 0.71 | TSHR (0.40) | — | |
| SCHEMBL5071464 | 0.69 | TSHR (0.43) | — | |
| SCHEMBL7076062 | 0.69 | TSHR (0.43) | — | |
| SCHEMBL221290 | 0.69 | — | — | |
| SCHEMBL5029222 | 0.69 | — | — | |
| SCHEMBL83524 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002087587-A2 | 4-AMINOSULFONYLQUINAZOLINES AND -QUINOLINES AS TYROSINE KINASE INHIBITORS | CELLTECH R & D LIMITED (GB) | 2002-11-07 | — | — | WO | disclosed |
| US-5191119-A | Process for producing non-ionic radiographic contrast media utilizing N-allylation | COOK IMAGING CORP. (US) | 1993-03-02 | — | — | US | disclosed |
| WO-1993003073-A1 | AZO POLYMERS FOR REVERSIBLE OPTICAL STORAGE | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 1993-02-18 | — | — | WO | disclosed |
| US-5151516-A | Unsaturated monomers | BASF AKTIENGESELLSCHAFT (DE) | 1992-09-29 | — | — | US | disclosed |
| EP-0160036-A4 | NOVEL SYNTHETIC METHODS FOR NON-IONIC RADIOGRAPHIC CONTRAST MEDIA. | BIOPHYSICA FOUNDATION (US) | 1987-06-11 | — | — | EP | disclosed |
| EP-0160036-A1 | NOVEL SYNTHETIC METHODS FOR NON-IONIC RADIOGRAPHIC CONTRAST MEDIA | BIOPHYSICA FOUNDATION (US) | 1985-11-06 | — | — | EP | disclosed |
| WO-1985001727-A1 | NOVEL SYNTHETIC METHODS FOR NON-IONIC RADIOGRAPHIC CONTRAST MEDIA | BIOPHYSICA FOUNDATION (US) | 1985-04-25 | — | — | WO | disclosed |