Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL949982 | 0.76 | KCNA5 (0.46) | CYP1A2 | |
| SCHEMBL7717140 | 0.76 | CTDSP1 (0.36) | CTDSP1CYP1A2P2RX7FAAH | |
| SCHEMBL12469850 | 0.75 | GOT1 (0.34) | CTDSP1CYP1A2P2RX7FAAH | |
| SCHEMBL22460414 | 0.73 | TSHR (0.36) | CTDSP1CYP1A2P2RX7 | |
| SCHEMBL8819171 | 0.73 | TSHR (0.36) | CTDSP1CYP1A2P2RX7 | |
| SCHEMBL12464826 | 0.73 | TSHR (0.36) | CTDSP1CYP1A2P2RX7 | |
| SCHEMBL7718073 | 0.72 | P2RX7 (0.35) | CTDSP1CYP1A2P2RX7FAAH | |
| SCHEMBL26666923 | 0.69 | KCNA5 (0.32) | CTDSP1CYP1A2P2RX7FAAH | |
| SCHEMBL27133573 | 0.69 | TSHR (0.33) | CTDSP1CYP1A2P2RX7 | |
| SCHEMBL2436106 | 0.69 | P2RX7 (0.41) | CTDSP1CYP1A2P2RX7FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002087587-A2 | 4-AMINOSULFONYLQUINAZOLINES AND -QUINOLINES AS TYROSINE KINASE INHIBITORS | CELLTECH R & D LIMITED (GB) | 2002-11-07 | — | — | WO | disclosed |