Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.41 |
| ▸ | KDM5A | P29375 | 4/20 | 0.41 |
| ▸ | ALKBH5 | Q6P6C2 | 10/20 | 0.40 |
| ▸ | KDM4A | O75164 | 2/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7717357 | 0.72 | KDM4E (0.46) | ALKBH5KDM4A | |
| SCHEMBL7711791 | 0.72 | KDM4E (0.63) | ALKBH5 | |
| SCHEMBL2267926 | 0.70 | APOBEC3A (0.38) | KDM4CKDM2BKDM5AALKBH5HCAR2 | |
| SCHEMBL7716604 | 0.70 | RAD51 (0.58) | ADORA3KDM5B | |
| SCHEMBL7711899 | 0.69 | KDM5B (0.46) | ALKBH5KDM5B | |
| SCHEMBL2268676 | 0.67 | ALKBH5 (0.40) | ALKBH5HCAR2 | |
| SCHEMBL7711920 | 0.67 | SMN1; SMN2 (0.33) | KDM4CKDM2BKDM5AADORA3KDM5B | |
| SCHEMBL7719466 | 0.66 | TSHR (0.40) | ALKBH5 | |
| SCHEMBL2271082 | 0.65 | TP53 (0.41) | ALKBH5ADORA3 | |
| SCHEMBL1777015 | 0.64 | ALKBH5 (0.50) | ALKBH5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6379395-B1 | DYEING FOR HAIR DYE | L'OREAL S.A. (FR) | 2002-04-30 | — | — | US | claimed |
| EP-0888109-B1 | KERATIN FIBRE DYE COMPOSITION CONTAINING PYRAZOLO-PYRIMIDINEOXO COMPOUNDS, USE THEREOF AS DYE COUPLERS, AND DYEING METHODS | OREAL (FR) | 2000-08-30 | — | — | EP | claimed |
| US-6379395-B1 | DYEING FOR HAIR DYE | L'OREAL S.A. (FR) | 2002-04-30 | — | — | US | disclosed |