SCHEMBL1777015

SCHEMBL1777015

O=C(O)c1cc(=O)n(O)[nH]1

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALKBH5 Q6P6C2 14/20 0.50
ALOX15 P16050 1/20 0.44
NFKB1 P19838 1/20 0.44
BLM P54132 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
CYP2C19 P33261 1/20 0.38
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1267392 0.77 ALKBH5 (0.49) ALKBH5ALOX15NFKB1BLMSMN1; SMN2
SCHEMBL10903062 0.73 ALKBH5 (0.44) ALKBH5ALOX15NFKB1BLMSMN1; SMN2
SCHEMBL1942315 0.71 ALKBH5 (0.63) ALKBH5SMN1; SMN2ALDH1A1
SCHEMBL951472 0.71 ALKBH5 (0.73) ALKBH5BLMALDH1A1LMNATSHR
SCHEMBL11778855 0.70 ALKBH5 (0.49) ALKBH5ALOX15NFKB1BLMSMN1; SMN2
SCHEMBL9698760 0.70 SMN1; SMN2 (0.57) ALKBH5ALOX15NFKB1BLMSMN1; SMN2
SCHEMBL11778860 0.70 ALKBH5 (0.45) ALKBH5ALOX15NFKB1BLMSMN1; SMN2
SCHEMBL692076 0.69 ALDH1A1 (0.41) ALKBH5SMN1; SMN2ALDH1A1CYP2C19
SCHEMBL11784403 0.69 ALKBH5 (0.41) ALKBH5ALOX15NFKB1BLMSMN1; SMN2
SCHEMBL10787351 0.68 ALKBH5 (0.71) ALKBH5SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9526687-B2 Polymers based on sulfonic acids, amides and special cross-linking agents CLARIANT INTERNATIONAL LTD. (CH) 2016-12-27 US disclosed
US-20150342856-A1 Cationic Comb Copolymers, Preparation Thereof And Use Thereof In Cosmetic, Pharmaceutical And Dermatological Formulations CLARIANT FINANCE (BVI) LIMITED (VG) 2015-12-03 US disclosed
US-20140086854-A1 Polymers Based On Sulfonic Acids, Amides And Special Cross-Linking Agents CLARIANT FINANCE (BVI) LIMITED (VG) 2014-03-27 US disclosed
US-8329200-B2 Water in oil emulsion has moisturizer of glycerol, chitosan, Fucogel, propylene glycol, polyoxyethylene glycol, dipropylene glycol, butylene glycol, mannitol, lactic acid, glycine,, sodium 2-pyrrolidone-5-carboxylate, hyaluronic acid, urea, and/or salts; storage stability; acne, wrinkle resistance BEIERSDORF AG (DE) 2012-12-11 US disclosed
US-20120114571-A1 Cationic Comb Copolymers, Preparation Thereof And Use Thereof In Cosmetic, Pharmaceutical And Dermatological Formulations CLARIANT FINANCE (BVI) LIMITED (VG) 2012-05-10 US disclosed
US-7943662-B2 For skin/hair light protection; cosmetics MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2011-05-17 US disclosed
US-20100047296-A1 Low-Residue Cosmetic Or Dermatological Stick Based On An Oil-In-Water Dispersion/Emulsion III HENKEL AG & CO. KGAA (DE) 2010-02-25 US disclosed
US-7658936-B2 Long term stability; low viscosity; minimal emulsifier content; oil in water soluton containing fatty alcohols, citric acid and partially neutralized monoglyceride and/or diglyceride fatty esters GOLDSCHMIDT GMBH (DE) 2010-02-09 US disclosed
US-7592000-B2 Method of tanning human body by mysting or immersion at elevated temperature MERCK PATENT GMBH (DE) 2009-09-22 US disclosed
US-20090156485-A1 METHOD FOR COUPLING KERATIN-BINDING POLYPEPTIDES WITH EFFECTOR MOLECULES WHICH SUPPORT CARBOXYLIC GROUPS OR SULFONIC ACID GROUPS BASE SE (DE) 2009-06-18 US disclosed
US-20080075684-A1 Keratin-Binding Polypeptides BASF AKTIENGESELLSCHAFT (DE) 2008-03-27 US disclosed
US-20070079754-A1 Method of tanning human body by mysting or immersion at elevated temperature MERCK PATENT GMBH (DE) 2007-04-12 US disclosed
US-20070031361-A1 Cosmetic, pharmaceutical and dermatological preparations comprising homopolymer and/or copolymer waxes of the monomers ethylene and/or propylene HERRMANN HANS-FRIEDRICH 2007-02-08 US disclosed
US-20060188459-A1 Cosmetic, pharmaceutical or dermatological preparations comprising copolymer waxes HEINRICHS FRANZ-LEO 2006-08-24 US disclosed
US-20060104940-A1 Cosmetic, pharmaceutical and dermatological preparations comprising copolymer waxes CLARIANT GMBH 2006-05-18 US disclosed
US-7037511-B1 Hydrous cosmetic or pharmaceutical sticks BEIERSDORF AG (DE) 2006-05-02 US disclosed
US-20060045856-A1 Composition containing a dihydroxyacetone precursor MERCK PATENT GMBH (DE) 2006-03-02 US disclosed
US-20050214333-A1 Cosmetic with sensitive ingredients BEIERSDORF AG 2005-09-29 US disclosed
US-20050201969-A1 Stable cosmetics BEIERSDORF AG 2005-09-15 US disclosed
US-20050074471-A1 Self-foaming or foamy preparations comprising particulate hydrophobic and/or hydrophobized and/or oil-absorbent solid substances BEIERSDORF AG (DE) 2005-04-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070031361-A1 Cosmetic, pharmaceutical and dermatological preparations comprising homopolymer and/or copolymer waxes of the monomers ethylene and/or propylene PMS2, MSH2, PGM2 ALKBH5 3510/4885ALOX15 184/4885NFKB1 2073/4885
US-20050074471-A1 Self-foaming or foamy preparations comprising particulate hydrophobic and/or hydrophobized and/or oil-absorbent solid substances HBB, HBG1, FFAR1 ALKBH5 1669/4885ALOX15 70/4885NFKB1 785/4885
US-20060104940-A1 Cosmetic, pharmaceutical and dermatological preparations comprising copolymer waxes CUTA, ACMSD, DEGS1 ALKBH5 1263/4885ALOX15 24/4885NFKB1 2661/4885
US-20090156485-A1 METHOD FOR COUPLING KERATIN-BINDING POLYPEPTIDES WITH EFFECTOR MOLECULES WHICH SUPPORT CARBOXYLIC GROUPS OR SULFONIC ACID GROUPS KRT18, KRTCAP2, CUTA ALKBH5 3111/4885ALOX15 4098/4885NFKB1 2715/4885
US-20140086854-A1 Polymers Based On Sulfonic Acids, Amides And Special Cross-Linking Agents ACMSD, SRM, TAS1R1 ALKBH5 2084/4885ALOX15 2335/4885NFKB1 2673/4885
US-20150342856-A1 Cationic Comb Copolymers, Preparation Thereof And Use Thereof In Cosmetic, Pharmaceutical And Dermatological Formulations C9, PARN, SGMS1 ALKBH5 1021/4885ALOX15 89/4885NFKB1 1757/4885
US-20060045856-A1 Composition containing a dihydroxyacetone precursor TYR, CUTA, DERA ALKBH5 2963/4885ALOX15 414/4885NFKB1 1975/4885
US-20100047296-A1 Low-Residue Cosmetic Or Dermatological Stick Based On An Oil-In-Water Dispersion/Emulsion III TYR, POLR1C, CUTA ALKBH5 1066/4885ALOX15 553/4885NFKB1 4503/4885
US-20120114571-A1 Cationic Comb Copolymers, Preparation Thereof And Use Thereof In Cosmetic, Pharmaceutical And Dermatological Formulations C9, PARN, SGMS1 ALKBH5 809/4885ALOX15 74/4885NFKB1 1533/4885
US-20070079754-A1 Method of tanning human body by mysting or immersion at elevated temperature TYR, CUTA, TREH ALKBH5 1711/4885ALOX15 1952/4885NFKB1 1487/4885
US-20050214333-A1 Cosmetic with sensitive ingredients CUTA, MITF, NISCH ALKBH5 2872/4885ALOX15 1896/4885NFKB1 4127/4885
US-20060188459-A1 Cosmetic, pharmaceutical or dermatological preparations comprising copolymer waxes CUTA, DEGS1, DSG1 ALKBH5 2850/4885ALOX15 65/4885NFKB1 2144/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.