Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.59 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | TERT | O14746 | 3/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
| ▸ | PPARD | Q03181 | 3/20 | 0.47 |
| ▸ | PPARA | Q07869 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | FABP4 | P15090 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10410016 | 1.00 | FAAH (0.59) | FAAHTRPV1TSHRSMN1; SMN2TERT | |
| SCHEMBL7719572 | 1.00 | FAAH (0.59) | FAAHTRPV1TSHRSMN1; SMN2TERT | |
| SCHEMBL10382124 | 1.00 | FAAH (0.59) | FAAHTRPV1TSHRSMN1; SMN2TERT | |
| Hydrochloric Acid SCHEMBL5167935 | 0.98 | FAAH (0.57) | FAAHTRPV1TSHRSMN1; SMN2TERT | |
| SCHEMBL17062961 | 0.96 | FAAH (0.55) | FAAHTRPV1TSHRSMN1; SMN2TERT | |
| SCHEMBL1840042 | 0.96 | FAAH (0.55) | FAAHTRPV1TSHRSMN1; SMN2TERT | |
| SCHEMBL17062960 | 0.96 | FAAH (0.55) | FAAHTRPV1TSHRSMN1; SMN2TERT | |
| SCHEMBL30457618 | 0.96 | FAAH (0.55) | FAAHTRPV1TSHRSMN1; SMN2TERT | |
| SCHEMBL27886133 | 0.96 | FAAH (0.55) | FAAHTRPV1TSHRSMN1; SMN2TERT | |
| SCHEMBL16776526 | 0.94 | TRPV1 (0.58) | FAAHTRPV1TSHRPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6387395-B1 | N-[1, (1-1) -dialkyloxy] - and N- [1, (1-1) -dialkenyloxy]- alk-1-yl-N,N,N-tetrasubstituted ammonium lipids and uses therefor | EPPSTEIN DEBORAH A (US) | 2002-05-14 | — | — | US | disclosed |
| US-5622712-A | CONSISTS OF A DRUG AND A QUATERNARY AMMONIUM SALT COMPOUND AS A LIPID COMPONENT | SYNTEX (U.S.A.) INC. (US) | 1997-04-22 | — | — | US | disclosed |
| US-5550289-A | FOR DNA TRANSFECTION | SYNTEX (U.S.A.) INC. (US) | 1996-08-27 | — | — | US | disclosed |
| US-5366737-A | Drug delivery, DNA transfection | SYNTEX (U.S.A.) INC. (US) | 1994-11-22 | — | — | US | disclosed |
| US-5049386-A | Drug and DNA delivery | SYNTEX (U.S.A.) INC. (US) | 1991-09-17 | — | — | US | disclosed |
| EP-0172007-B1 | STABLE LIPOSOMES WITH AQUEOUS-SOLUBLE MEDICAMENTS AND METHODS FOR THEIR PREPARATION | SYNTEX (U.S.A.) INC. (US) | 1991-05-22 | — | — | EP | disclosed |
| US-4946787-A | DOUBLE COATED LIPOSOME COMPLEX MADE UP OF POLYANION AND A LIPID | SYNTEX (U.S.A.) INC. (US) | 1990-08-07 | — | — | US | disclosed |
| EP-0187702-B1 | N-(OMEGA,OMEGA-1-DIALKOXY)- AND N-(OMEGA,OMEGA-1-DIALKENOXY)-ALK-1-YL-N,N,N-TRISUBSTITUTED AMMONIUM SURFACTANTS, THEIR PREPARATION AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM | SYNTEX (U.S.A.) INC. (US) | 1990-03-14 | — | — | EP | disclosed |
| US-4897355-A | LIPISOME-POLYANION COMPLEX | SYNTEX (U.S.A.) INC. (US) | 1990-01-30 | — | — | US | disclosed |
| EP-0188311-A2 | Pharmaceutical formulation of nicardipine and 1,2-dioxy-omega-trialkylammonium compounds | SYNTEX (U.S.A.) INC. (US) | 1986-07-23 | — | — | EP | disclosed |
| EP-0187702-A1 | N-(omega,omega-1-dialkoxy)- and N-(omega,omega-1-dialkenoxy)-alk-1-yl-N,N,N-trisubstituted ammonium surfactants, their preparation and pharmaceutical formulations containing them | SYNTEX (U.S.A.) INC. (US) | 1986-07-16 | — | — | EP | disclosed |
| EP-0172007-A2 | Stable liposomes with aqueous-soluble medicaments and methods for their preparation | SYNTEX (U.S.A.) INC. (US) | 1986-02-19 | — | — | EP | disclosed |