Hydrochloric Acid

Hydrochloric Acid

SCHEMBL5167935

CCCCCCCCC=CCCCCCCC(C=O)CCCCCC.Cl.Cl

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG known ✓ P37231 3/20 0.46
CHRM1 known ✓ P11229 1/20 0.46
TOP1 known ✓ P11387 1/20 0.46
CYP19A1 known ✓ P11511 1/20 0.46
PTGS1 known ✓ P23219 1/20 0.46
SLC6A2 known ✓ P23975 1/20 0.46
FLT3 known ✓ P36888 1/20 0.46
KCNH2 known ✓ Q12809 1/20 0.46
FAAH O00519 4/20 0.57
TRPV1 Q8NER1 2/20 0.57
TSHR P16473 2/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
TERT O14746 3/20 0.46
PTPN1 P18031 3/20 0.46
PPARD Q03181 3/20 0.46
PPARA Q07869 3/20 0.46
CYP1A2 P05177 2/20 0.46
MAPT P10636 2/20 0.46
CYP2C19 P33261 2/20 0.46
BLM P54132 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10382124 0.98 FAAH (0.59) FAAHTRPV1TSHRSMN1; SMN2TERT
SCHEMBL10410016 0.98 FAAH (0.59) FAAHTRPV1TSHRSMN1; SMN2TERT
SCHEMBL7719569 0.98 FAAH (0.59) FAAHTRPV1TSHRSMN1; SMN2TERT
SCHEMBL7719572 0.98 FAAH (0.59) FAAHTRPV1TSHRSMN1; SMN2TERT
SCHEMBL1840042 0.94 FAAH (0.55) FAAHTRPV1TSHRSMN1; SMN2TERT
SCHEMBL30457618 0.94 FAAH (0.55) FAAHTRPV1TSHRSMN1; SMN2TERT
SCHEMBL27886133 0.94 FAAH (0.55) FAAHTRPV1TSHRSMN1; SMN2TERT
SCHEMBL17062960 0.94 FAAH (0.55) FAAHTRPV1TSHRSMN1; SMN2TERT
SCHEMBL17062961 0.94 FAAH (0.55) FAAHTRPV1TSHRSMN1; SMN2TERT
SCHEMBL16776526 0.92 TRPV1 (0.58) FAAHTRPV1TSHRPPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1249471-B1 Polypropylene-based resins and polypropylene-based resin compositions PRIME POLYMER CO LTD (JP) 2013-06-26 EP disclosed
EP-0893247-B1 DECORATIVE FILM OR SHEET, AND DECORATIVE MATERIAL AND BUILDING MATERIAL MADE BY USING THE SAME PRIME POLYMER CO LTD (JP) 2007-04-11 EP disclosed
EP-1273596-B1 FLEXIBLE POLYPROPYLENE RESIN IDEMITSU KOSAN CO (JP) 2005-03-30 EP disclosed
US-6855756-B2 Soft polypropylene resin having a melt index falling in a specific range, prepared by melting and kneading a propylene homo or copolymer each having specific properties in presence of a radical generating agent IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2005-02-15 US disclosed
US-6617008-B1 Decorative film or sheet, and decorative material and building material made by using the same IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2003-09-09 US disclosed
US-6545072-B2 Phenolic antioxidant 1,3,5-tris(4-t-butyl-3-hydroxy-2,6-dimethylbenzyl) isocyanurate and a hindered amine light stabilizer; little discoloration when exposed to relatively high temperatures IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2003-04-08 US disclosed
US-6545069-B2 Ultraviolet radiation shields IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2003-04-08 US disclosed
US-20030055137-A1 Soft polypropylene resin having a melt index falling in a specific range, prepared by melting and kneading a propylene homo or copolymer each having specific properties in presence of a radical generating agent PRIME POLYMER CO., LTD. (JP) 2003-03-20 US disclosed
EP-0927743-B1 FLEXIBLE POLYPROPYLENE RESIN COMPOSITIONS, FILMS OR SHEETS MADE THEREFROM, AND SURFACE-PROTECTIVE FILMS OR SHEETS MADE THEREFROM IDEMITSU PETROCHEMICAL CO (JP) 2003-03-19 EP disclosed
EP-1273596-A1 FLEXIBLE POLYPROPYLENE RESIN IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2003-01-08 EP disclosed
EP-0784074-B1 PROPYLENE RESIN COMPOSITION FOR INTERIOR MATERIAL FOR AUTOMOBILES, AND INTERIOR MATERIAL FOR AUTOMOBILES IDEMITSU PETROCHEMICAL CO (JP) 1999-07-07 EP disclosed
EP-0893247-A1 DECORATIVE FILM OR SHEET, AND DECORATIVE MATERIAL AND BUILDING MATERIAL MADE BY USING THE SAME IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1999-01-27 EP disclosed
EP-0744439-B1 Polypropylene composition comprising lubricants for calendering IDEMITSU PETROCHEMICAL CO (JP) 1998-12-09 EP disclosed
US-5777056-A CATALYTIC POLYMERIZATION OF PROPYLENE FOR HEAT RESISTANT POLYMERS IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1998-07-07 US disclosed
EP-0693524-B1 Polypropylene resin and film prepared therefrom IDEMITSU PETROCHEMICAL CO (JP) 1998-06-10 EP disclosed
EP-0825228-A2 Polypropylene-based resins and polypropylene-based resin compositions IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1998-02-25 EP disclosed
EP-0784074-A1 PROPYLENE RESIN COMPOSITION FOR INTERIOR MATERIAL FOR AUTOMOBILES, AND INTERIOR MATERIAL FOR AUTOMOBILES IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1997-07-16 EP disclosed
EP-0744439-A1 Polypropylene composition comprising lubricants for calendering IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1996-11-27 EP disclosed
EP-0693524-A1 Polypropylene resin and film prepared therefrom IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1996-01-24 EP disclosed
EP-0606618-A2 A polyolefinic resin and a resin composition comprising said resin IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1994-07-20 EP disclosed