Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.57 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.57 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.57 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.52 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | GPR6 | P46095 | 2/20 | 0.52 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | UBE2N | P61088 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | GPR183 | P32249 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.47 |
| ▸ | MLYCD | O95822 | 1/20 | 0.47 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1375337 | 0.90 | SIGMAR1 (0.64) | PDK1PDK2PDK3PDK4SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7718789 | 0.88 | SIGMAR1 (0.62) | PDK1PDK2PDK3PDK4SIGMAR1 | |
| Trifluoroacetic Acid SCHEMBL31098156 | 0.88 | SIGMAR1 (0.55) | PDK1PDK2PDK3PDK4SIGMAR1 | |
| Trifluoroacetic Acid SCHEMBL27832857 | 0.84 | SIGMAR1 (0.81) | SIGMAR1PKMHPGDMKNK1MKNK2 | |
| Trifluoroacetic Acid SCHEMBL15565817 | 0.83 | HPGD (0.63) | SIGMAR1PKMHPGDMKNK2RAD52 | |
| Trifluoroacetic Acid SCHEMBL16150177 | 0.83 | SIGMAR1 (0.59) | SIGMAR1PKMHPGDMKNK1MKNK2 | |
| Trifluoroacetic Acid SCHEMBL3961759 | 0.81 | SIGMAR1 (0.61) | SIGMAR1PKMHPGDMKNK1MKNK2 | |
| Trifluoroacetic Acid SCHEMBL7718796 | 0.79 | GPR6 (0.51) | PDK1PDK2PDK3PDK4CYP3A4 | |
| Trifluoroacetic Acid SCHEMBL7718799 | 0.79 | GPR6 (0.51) | PDK1PDK2PDK3PDK4CYP3A4 | |
| Trifluoroacetic Acid SCHEMBL6199874 | 0.78 | L3MBTL1 (0.62) | SIGMAR1PKMHPGDMKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384222-B1 | BRADYKININ HORMONE ANTAGONIST; ANALGESIC, ANTIINFLAMMATORY; ASTHMA, CEREBRAL TRAUMATIC SHOCK AND ALLERGIC RHINITIS; ETHERIFICATION, AMIDATION | FOURNIER INDUSTRIE ET SANTE (FR) | 2002-05-07 | — | — | US | disclosed |