Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CA4 | P22748 | 1/20 | 0.59 |
| ▸ | CA5A | P35218 | 1/20 | 0.59 |
| ▸ | CA7 | P43166 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.59 |
| ▸ | BCHE | P06276 | 2/20 | 0.54 |
| ▸ | ACHE | P22303 | 2/20 | 0.54 |
| ▸ | BACE1 | P56817 | 2/20 | 0.54 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.53 |
| ▸ | EED | O75530 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7725283 | 0.90 | CA12 (0.62) | CA12CA1CA2CA4CA5A | |
| SCHEMBL26705313 | 0.88 | CA12 (0.60) | CA12CA1CA2CA4CA5A | |
| SCHEMBL916913 | 0.83 | CA12 (0.71) | CA12CA1CA2CA4CA5A | |
| SCHEMBL7724043 | 0.80 | HTR2A (0.51) | BCHEACHEBACE1EED | |
| SCHEMBL7725316 | 0.80 | HTR2A (0.51) | BCHEACHEBACE1EED | |
| SCHEMBL18609761 | 0.80 | CA12 (0.67) | CA12CA1CA2CA4CA5A | |
| SCHEMBL1818246 | 0.79 | KDM4E (0.66) | CA12CA1CA2CA4CA5A | |
| SCHEMBL5872263 | 0.79 | KDM4E (0.52) | CA12CA1CA2CA4CA5A | |
| SCHEMBL5871587 | 0.79 | KDM4E (0.52) | CA12CA1CA2CA4CA5A | |
| SCHEMBL7546010 | 0.79 | CARM1 (0.56) | CA12CA1CA2CA4CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6468998-B1 | ANTAGONIZE SEROTONIN 2 RECEPTORS, SUPPRESS PLATELET AGGREGATION, IMPROVE PERIPHERAL CIRCULATION AND PROMOTE LACHRYMATION | MITSUBISHI PHARMA CORPORATION (JP) | 2002-10-22 | — | — | US | disclosed |
| EP-1125922-A1 | PYRROLIDINE COMPOUNDS AND MEDICINAL UTILIZATION THEREOF | Welfide Corporation (JP) | 2001-08-22 | — | — | EP | disclosed |