Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.56 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA5A | P35218 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | CCR2 | P41597 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7725283 | 0.84 | CA12 (0.62) | CARM1PRMT6CA12CA1CA2 | |
| SCHEMBL2575970 | 0.81 | CARM1 (0.59) | CARM1PRMT6CA12CA1CA2 | |
| SCHEMBL11577417 | 0.80 | HTR1A (0.58) | CARM1PRMT6KDM1ASIGMAR1 | |
| SCHEMBL331018 | 0.79 | BCHE (0.68) | MAPK1ALDH1A1ROCK2CCR2ROCK1 | |
| SCHEMBL331017 | 0.79 | BCHE (0.68) | MAPK1ALDH1A1ROCK2CCR2ROCK1 | |
| SCHEMBL7719804 | 0.79 | CA12 (0.59) | CA12CA1CA2CA4CA5A | |
| SCHEMBL16514503 | 0.76 | CARM1 (0.50) | CARM1PRMT6MAPK1SLC18A3KDM1A | |
| SCHEMBL916913 | 0.76 | CA12 (0.71) | CARM1PRMT6CA12CA1CA2 | |
| SCHEMBL11236449 | 0.75 | CARM1 (0.55) | CARM1PRMT6KDM1ACA12CA1 | |
| SCHEMBL11575616 | 0.74 | HTR7 (0.54) | CARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001030745-A1 | ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-03 | — | — | WO | disclosed |