Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | HTR2C | P28335 | 2/20 | 0.51 |
| ▸ | HTR7 | P34969 | 2/20 | 0.51 |
| ▸ | HTR6 | P50406 | 1/20 | 0.51 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.49 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | EED | O75530 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7725316 | 1.00 | HTR2A (0.51) | HTR2AHTR2CHTR7HTR6CARM1 | |
| SCHEMBL27763800 | 0.92 | HTR2A (0.56) | HTR2AHTR2CHTR7HTR6CARM1 | |
| Hydrochloric Acid SCHEMBL29280917 | 0.91 | HTR2A (0.55) | HTR2AHTR2CHTR7HTR6CARM1 | |
| SCHEMBL7723966 | 0.84 | ACHE (0.61) | CARM1PRMT6BCHEACHEBACE1 | |
| SCHEMBL7719804 | 0.80 | CA12 (0.59) | BCHEACHEBACE1EED | |
| SCHEMBL12993065 | 0.80 | HTR2A (0.59) | HTR2AHTR2CHTR7HTR6 | |
| SCHEMBL8151042 | 0.80 | BCHE (0.62) | BCHEACHEBACE1 | |
| SCHEMBL7723203 | 0.78 | HTR2A (0.54) | HTR2AHTR2CHTR7HTR6MAOA | |
| SCHEMBL3601901 | 0.78 | HTR2A (0.54) | HTR2AHTR2CHTR7HTR6MAOA | |
| SCHEMBL20459540 | 0.78 | HRH3 (0.53) | HTR2AHTR2CHTR7ACHEHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6468998-B1 | ANTAGONIZE SEROTONIN 2 RECEPTORS, SUPPRESS PLATELET AGGREGATION, IMPROVE PERIPHERAL CIRCULATION AND PROMOTE LACHRYMATION | MITSUBISHI PHARMA CORPORATION (JP) | 2002-10-22 | — | — | US | disclosed |
| EP-1125922-A1 | PYRROLIDINE COMPOUNDS AND MEDICINAL UTILIZATION THEREOF | Welfide Corporation (JP) | 2001-08-22 | — | — | EP | disclosed |