SCHEMBL7719905

SCHEMBL7719905

NC1=NN(c2ccccc2)CC1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.58
PTGS1 P23219 1/20 0.58
PTGS2 P35354 1/20 0.58
MAPT P10636 5/20 0.58
KDM4E B2RXH2 4/20 0.58
MAPK1 P28482 4/20 0.58
NPC1 O15118 3/20 0.58
RAB9A P51151 3/20 0.58
GLA P06280 2/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
TDP1 Q9NUW8 1/20 0.58
ABL1 P00519 1/20 0.56
MAOB P27338 2/20 0.50
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
SIGMAR1 Q99720 3/20 0.42
ALDH1A1 P00352 4/20 0.40
GAA P10253 4/20 0.40
LMNA P02545 1/20 0.37
HPGD P15428 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11103110 0.98 ALOX5 (0.57) ALOX5PTGS1PTGS2MAPTKDM4E
Sulfuric Acid SCHEMBL11106611 0.89 ALOX5 (0.50) ALOX5PTGS1PTGS2MAPTKDM4E
SCHEMBL2268832 0.83 ABL1 (0.61) ALOX5PTGS1PTGS2MAPTKDM4E
SCHEMBL10657208 0.82 ABL1 (0.54) ALOX5PTGS1PTGS2MAPTKDM4E
SCHEMBL2271194 0.80 ABL1 (0.57) ALOX5PTGS1PTGS2MAPTKDM4E
SCHEMBL908024 0.80 ABL1 (0.67) ALOX5PTGS1PTGS2MAPTKDM4E
SCHEMBL7719900 0.80 ABL1 (0.57) ALOX5PTGS1PTGS2MAPTKDM4E
SCHEMBL7714604 0.80 ABL1 (0.57) ALOX5PTGS1PTGS2MAPTKDM4E
SCHEMBL7717944 0.80 ABL1 (0.57) ALOX5PTGS1PTGS2MAPTKDM4E
SCHEMBL7718654 0.80 ABL1 (0.57) ALOX5PTGS1PTGS2MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102797043-B Medicinal molecular fragment library and construction process thereof Tianli (Tianjin) Technology Co., Ltd. (CN) 2015-11-25 CN claimed
CN-102797043-A Medicinal molecular fragment library and construction method thereof CBB NETWORK CO LTD 2012-11-28 CN claimed
US-6387136-B1 OXIDATION COLOR DYES AND COUPLER L'OREAL S.A. (FR) 2002-05-14 US claimed
EP-0974337-B1 Keratinous fibre dyeing compositions containing 3-amino pyrazoline derivatives as coupling agents, process for dyeing and dyeing kit OREAL (FR) 2001-03-21 EP claimed
EP-0974337-A1 Keratinous fibre dyeing compositions containing 3-amino pyrazoline derivatives as coupling agents, process for dyeing and dyeing kit L'OREAL (FR) 2000-01-26 EP claimed
US-4149005-A Process for preparing 1-phenyl-3-aminopyrazoles MONTEDISON S.P.A. (IT) 1979-04-10 US claimed
CN-120527094-B Medium-voltage fireproof cable and preparation method thereof 广州电缆有限公司 2026-02-17 CN disclosed
EP-4656638-A2 PYRAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF Japan Tobacco Inc. (JP) 2025-12-03 EP disclosed
CN-120527094-A Medium-voltage fireproof cable and preparation method thereof 广州电缆有限公司 2025-08-22 CN disclosed
US-20230348438-A1 PYRAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF JAPAN TOBACCO INC. (JP) 2023-11-02 US disclosed
US-20230348438-A1 PYRAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF JAPAN TOBACCO INC. (JP) 2023-11-02 US disclosed
US-20230348438-A1 PYRAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF JAPAN TOBACCO INC. (JP) 2023-11-02 US disclosed
US-20200317644-A1 PYRAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF JAPAN TOBACCO INC (JP) 2020-10-08 US disclosed
US-4308205-A RED OR ORANGE SHADES ON POLYACRYLONITRILE MONTEDISON S.P.A. (IT) 1981-12-29 US disclosed
US-4268436-A OXIDATIVE DIAZOTIZATION WITH NITROSYLSULFURIC ACID, ALKALINE METAL NITRITES, OR ALKYL NITRITES AZIENDE COLORI NAZIONALI AFFINI ACNA S.P.A. (IT) 1981-05-19 US disclosed
US-4263204-A FOR PRINTING SYNTHETIC FIBERS MONTEDISON S.P.A. (IT) 1981-04-21 US disclosed
EP-0022578-A1 Pharmaceutical compositions containing 3-Amino-pyrazoline derivatives THE WELLCOME FOUNDATION LIMITED (GB) 1981-01-21 EP disclosed
US-4216145-A Water-insoluble mono-azo yellow dyes derived from 1-phenyl-3-aminopyrazoles MONTEDISON S.P.A. (IT) 1980-08-05 US disclosed
EP-0011295-A1 Yellow monoazo dyes of the 2-hydroxydibenzofuran series; their preparation and use for dyeing and printing synthetic hydrophobic fibres Montedison S.p.A. (IT) 1980-05-28 EP disclosed
US-4149005-A Process for preparing 1-phenyl-3-aminopyrazoles MONTEDISON S.P.A. (IT) 1979-04-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230348438-A1 PYRAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF CYP2C19, CYP3A7, CYP3A5 ALOX5 3198/4885PTGS1 2650/4885PTGS2 2522/4885
US-20200317644-A1 PYRAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF CYP2C19, CYP3A7, CYP3A5 ALOX5 3198/4885PTGS1 2650/4885PTGS2 2522/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.