Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NQO1 | P15559 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7719317 | 0.84 | ALOX5 (0.55) | ABL1LMNATSHRNPC1MEN1 | |
| SCHEMBL7718650 | 0.82 | ABL1 (0.53) | ABL1LMNATDP1KMT2AMAPT | |
| SCHEMBL10733723 | 0.80 | RAB9A (0.51) | ABL1LMNANPC1MEN1KMT2A | |
| SCHEMBL7714604 | 0.76 | ABL1 (0.57) | ABL1LMNATDP1NPC1MEN1 | |
| SCHEMBL2268832 | 0.76 | ABL1 (0.61) | ABL1LMNATDP1NPC1MEN1 | |
| SCHEMBL8017820 | 0.73 | ABL1 (0.54) | ABL1TDP1NPC1MAPTRAB9A | |
| SCHEMBL7717944 | 0.73 | ABL1 (0.57) | ABL1LMNATDP1NPC1MEN1 | |
| SCHEMBL2271194 | 0.73 | ABL1 (0.57) | ABL1TDP1NPC1MEN1KMT2A | |
| SCHEMBL7719900 | 0.73 | ABL1 (0.57) | ABL1TSHRTDP1NPC1MAPT | |
| SCHEMBL908024 | 0.73 | ABL1 (0.67) | ABL1LMNATDP1NPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6387136-B1 | OXIDATION COLOR DYES AND COUPLER | L'OREAL S.A. (FR) | 2002-05-14 | — | — | US | claimed |
| EP-0974337-B1 | Keratinous fibre dyeing compositions containing 3-amino pyrazoline derivatives as coupling agents, process for dyeing and dyeing kit | OREAL (FR) | 2001-03-21 | — | — | EP | claimed |
| EP-0974337-A1 | Keratinous fibre dyeing compositions containing 3-amino pyrazoline derivatives as coupling agents, process for dyeing and dyeing kit | L'OREAL (FR) | 2000-01-26 | — | — | EP | claimed |
| US-6387136-B1 | OXIDATION COLOR DYES AND COUPLER | L'OREAL S.A. (FR) | 2002-05-14 | — | — | US | disclosed |
| EP-0974337-B1 | Keratinous fibre dyeing compositions containing 3-amino pyrazoline derivatives as coupling agents, process for dyeing and dyeing kit | OREAL (FR) | 2001-03-21 | — | — | EP | disclosed |
| EP-0974337-A1 | Keratinous fibre dyeing compositions containing 3-amino pyrazoline derivatives as coupling agents, process for dyeing and dyeing kit | L'OREAL (FR) | 2000-01-26 | — | — | EP | disclosed |
| US-4268436-A | OXIDATIVE DIAZOTIZATION WITH NITROSYLSULFURIC ACID, ALKALINE METAL NITRITES, OR ALKYL NITRITES | AZIENDE COLORI NAZIONALI AFFINI ACNA S.P.A. (IT) | 1981-05-19 | — | — | US | disclosed |
| EP-0011295-A1 | Yellow monoazo dyes of the 2-hydroxydibenzofuran series; their preparation and use for dyeing and printing synthetic hydrophobic fibres | Montedison S.p.A. (IT) | 1980-05-28 | — | — | EP | disclosed |