Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 3/20 | 0.31 |
| ▸ | TOP1 | P11387 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | PPARD | Q03181 | 2/20 | 0.31 |
| ▸ | PPARA | Q07869 | 2/20 | 0.31 |
| ▸ | F7 | P08709 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | F3 | P13726 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | RECQL | P46063 | 2/20 | 0.30 |
| ▸ | BLM | P54132 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7805335 | 1.00 | HDAC6 (0.36) | HDAC6EPHX2PPARGTOP1ALDH1A1 | |
| SCHEMBL7719949 | 0.73 | EPHX2 (0.33) | HDAC6EPHX2PPARGTOP1ALDH1A1 | |
| SCHEMBL7805334 | 0.73 | EPHX2 (0.33) | HDAC6EPHX2PPARGTOP1ALDH1A1 | |
| SCHEMBL28675520 | 0.67 | HDAC6 (0.33) | HDAC6EPHX2KMT2ACYP1A2POLB | |
| SCHEMBL5381165 | 0.64 | TOP1 (0.58) | PPARGTOP1ALDH1A1CYP19A1KMT2A | |
| SCHEMBL5381163 | 0.64 | TOP1 (0.58) | PPARGTOP1ALDH1A1CYP19A1KMT2A | |
| SCHEMBL567545 | 0.62 | CA14 (0.31) | HDAC6HDAC1HDAC2 | |
| SCHEMBL25124155 | 0.62 | HDAC6 (0.33) | HDAC6TDP1 | |
| SCHEMBL29076008 | 0.62 | GABRP (0.34) | HDAC6CYP1A2CYP2C9CYP2C19HDAC1 | |
| SCHEMBL29076007 | 0.62 | GABRP (0.34) | HDAC6CYP1A2CYP2C9CYP2C19HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384026-B1 | Macrocyclic polyamine lactones and derivatives thereof and their use as arthropod repellents | CORNELL RESEARCH FOUNDATION, INC. | 2002-05-07 | — | — | US | disclosed |
| EP-1067921-A4 | MACROCYCLIC POLYAMINE LACTONES AND DERIVATIVES THEREOF AND THEIR USE AS ARTHROPOD REPELLENTS | CORNELL RES FOUNDATION INC (US) | 2001-06-27 | — | — | EP | disclosed |
| EP-1067921-A1 | MACROCYCLIC POLYAMINE LACTONES AND DERIVATIVES THEREOF AND THEIR USE AS ARTHROPOD REPELLENTS | CORNELL RESEARCH FOUNDATION (US) | 2001-01-17 | — | — | EP | disclosed |
| WO-1999051222-A1 | MACROCYCLIC POLYAMINE LACTONES AND DERIVATIVES THEREOF AND THEIR USE AS ARTHROPOD REPELLENTS | CORNELL RESEARCH FOUNDATION, INC. (US) | 1999-10-14 | — | — | WO | disclosed |