Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 3/20 | 0.31 |
| ▸ | TOP1 | P11387 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | PPARD | Q03181 | 2/20 | 0.31 |
| ▸ | PPARA | Q07869 | 2/20 | 0.31 |
| ▸ | F7 | P08709 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | F3 | P13726 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | RECQL | P46063 | 2/20 | 0.30 |
| ▸ | BLM | P54132 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7719949 | 1.00 | EPHX2 (0.33) | EPHX2HDAC6PPARGTOP1ALDH1A1 | |
| SCHEMBL7718969 | 0.86 | L3MBTL1 (0.30) | L3MBTL1 | |
| SCHEMBL7715986 | 0.84 | L3MBTL1 (0.36) | KMT2APOLBKDM4EMEN1MAPT | |
| SCHEMBL7719950 | 0.73 | HDAC6 (0.36) | EPHX2HDAC6PPARGTOP1ALDH1A1 | |
| SCHEMBL7805335 | 0.73 | HDAC6 (0.36) | EPHX2HDAC6PPARGTOP1ALDH1A1 | |
| SCHEMBL567560 | 0.72 | — | — | |
| SCHEMBL19560799 | 0.71 | CA14 (0.39) | HDAC6ALDH1A1 | |
| SCHEMBL28980352 | 0.70 | MEN1 (0.30) | KMT2AMEN1 | |
| SCHEMBL26049385 | 0.70 | L3MBTL1 (0.30) | HDAC6BLMHSD17B10L3MBTL1 | |
| SCHEMBL3183520 | 0.68 | L3MBTL1 (0.37) | CYP1A2CYP2D6LMNAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1067921-A4 | MACROCYCLIC POLYAMINE LACTONES AND DERIVATIVES THEREOF AND THEIR USE AS ARTHROPOD REPELLENTS | CORNELL RES FOUNDATION INC (US) | 2001-06-27 | — | — | EP | disclosed |
| EP-1067921-A1 | MACROCYCLIC POLYAMINE LACTONES AND DERIVATIVES THEREOF AND THEIR USE AS ARTHROPOD REPELLENTS | CORNELL RESEARCH FOUNDATION (US) | 2001-01-17 | — | — | EP | disclosed |
| WO-1999051222-A1 | MACROCYCLIC POLYAMINE LACTONES AND DERIVATIVES THEREOF AND THEIR USE AS ARTHROPOD REPELLENTS | CORNELL RESEARCH FOUNDATION, INC. (US) | 1999-10-14 | — | — | WO | disclosed |