Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1576324 | 0.79 | — | — | |
| SCHEMBL891346 | 0.76 | — | — | |
| SCHEMBL5709983 | 0.75 | THRB (0.59) | USP2THRBCYP3A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL22395412 | 0.75 | THRB (0.59) | USP2THRBCYP3A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL25389134 | 0.75 | THRB (0.59) | USP2THRBCYP3A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL25303278 | 0.75 | THRB (0.59) | USP2THRBCYP3A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL9278178 | 0.75 | THRB (0.59) | USP2THRBCYP3A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL4582841 | 0.74 | LMNA (0.36) | USP2THRBALDH1A1LMNA | |
| SCHEMBL4457448 | 0.72 | USP2 (0.62) | USP2THRBCYP3A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL9311248 | 0.72 | TSHR (0.41) | THRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6387395-B1 | N-[1, (1-1) -dialkyloxy] - and N- [1, (1-1) -dialkenyloxy]- alk-1-yl-N,N,N-tetrasubstituted ammonium lipids and uses therefor | EPPSTEIN DEBORAH A (US) | 2002-05-14 | — | — | US | disclosed |
| US-5622712-A | CONSISTS OF A DRUG AND A QUATERNARY AMMONIUM SALT COMPOUND AS A LIPID COMPONENT | SYNTEX (U.S.A.) INC. (US) | 1997-04-22 | — | — | US | disclosed |
| US-5550289-A | FOR DNA TRANSFECTION | SYNTEX (U.S.A.) INC. (US) | 1996-08-27 | — | — | US | disclosed |
| US-5545412-A | USING LIPOPHILIC COMPOUNDS TO TRANSFECT DNA AND FOR DRUG DELIVERY BY FORMING COMPLEXES TO PENETRATE CELLULAR MEMBRANES | SYNTEX (U.S.A.) INC. (US) | 1996-08-13 | — | — | US | disclosed |
| US-5366737-A | Drug delivery, DNA transfection | SYNTEX (U.S.A.) INC. (US) | 1994-11-22 | — | — | US | disclosed |
| US-5208036-A | Complexing a liposomal composition with a quaternary ammonium diether | SYNTEX (U.S.A.) INC. (US) | 1993-05-04 | — | — | US | disclosed |
| US-5049386-A | Drug and DNA delivery | SYNTEX (U.S.A.) INC. (US) | 1991-09-17 | — | — | US | disclosed |
| US-4897355-A | LIPISOME-POLYANION COMPLEX | SYNTEX (U.S.A.) INC. (US) | 1990-01-30 | — | — | US | disclosed |