Methyl Yellow

Methyl Yellow

SCHEMBL7720573

CN(C)c1ccc(N=Nc2ccccc2)cc1.O=S(=O)(Cl)Cl

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.78
TSHR P16473 3/20 0.78
MAPK1 P28482 3/20 0.78
TDP1 Q9NUW8 2/20 0.78
HSD17B10 Q99714 2/20 0.78
NPC1 O15118 7/20 0.59
KMT2A Q03164 6/20 0.59
RAB9A P51151 6/20 0.59
MEN1 O00255 5/20 0.59
POLB P06746 3/20 0.59
CA12 O43570 2/20 0.59
CA2 P00918 2/20 0.59
CA9 Q16790 2/20 0.59
MYC P01106 1/20 0.55
ALOX15 P16050 1/20 0.54
NSD2 O96028 1/20 0.54
CASP3 P42574 1/20 0.54
SENP8 Q96LD8 1/20 0.54
SENP7 Q9BQF6 1/20 0.54
SENP6 Q9GZR1 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethyl Yellow SCHEMBL7720567 1.00 ALDH1A1 (0.78) ALDH1A1TSHRMAPK1TDP1HSD17B10
Methyl Yellow SCHEMBL239712 0.88 ALDH1A1 (1.00) ALDH1A1TSHRMAPK1TDP1HSD17B10
SCHEMBL10909165 0.88 ALDH1A1 (1.00) ALDH1A1TSHRMAPK1TDP1HSD17B10
Dimethyl Yellow SCHEMBL187589 0.88 ALDH1A1 (1.00) ALDH1A1TSHRMAPK1TDP1HSD17B10
SCHEMBL8982839 0.88 ALDH1A1 (1.00) ALDH1A1TSHRMAPK1TDP1HSD17B10
SCHEMBL8982830 0.88 ALDH1A1 (1.00) ALDH1A1TSHRMAPK1TDP1HSD17B10
SCHEMBL8982833 0.88 ALDH1A1 (1.00) ALDH1A1TSHRMAPK1TDP1HSD17B10
Methyl Yellow SCHEMBL6240923 0.86 ALDH1A1 (0.95) ALDH1A1TSHRMAPK1TDP1HSD17B10
Dimethyl Yellow SCHEMBL6240921 0.86 ALDH1A1 (0.95) ALDH1A1TSHRMAPK1TDP1HSD17B10
Methyl Yellow SCHEMBL28233507 0.86 ALDH1A1 (0.95) ALDH1A1TSHRMAPK1TDP1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102971303-A Zn (Il) based colorimetric sensor and process for the preparation thereof COUNCIL SCIENT IND RES 2013-03-13 CN claimed
EP-3000897-B1 COLORECTAL CANCER PROGNOSIS AGENT KIT BIOMERIEUX SA (FR) 2019-10-16 EP disclosed
US-10072300-B2 Kit for the prognosis of colorectal cancer BIOMERIEUX (FR) 2018-09-11 US disclosed
US-20160177399-A1 A KIT FOR THE PROGNOSIS OF COLORECTAL CANCER BIOMERIEUX (FR) 2016-06-23 US disclosed
EP-3000897-A2 COLORECTAL CANCER PROGNOSIS AGENT KIT Biomérieux (FR) 2016-03-30 EP disclosed
CN-102971303-B Zn (Il) based colorimetric sensor and process for the preparation thereof COUNCIL SCIENT IND RES 2015-07-15 CN disclosed
EP-2576522-B1 ZN (II) BASED COLORIMETRIC SENSOR AND PROCESS FOR THE PREPARATION THEREOF COUNCIL SCIENT IND RES (IN) 2014-11-05 EP disclosed
US-20130130306-A1 ZN (II) BASED COLORIMETRIC SENSOR AND PROCESS FOR THE PREPARATION THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2013-05-23 US disclosed
EP-2576522-A1 ZN (II) BASED COLORIMETRIC SENSOR AND PROCESS FOR THE PREPARATION THEREOF Council of Scientific & Industrial Research (IN) 2013-04-10 EP disclosed
CN-102971303-A Zn (Il) based colorimetric sensor and process for the preparation thereof COUNCIL SCIENT IND RES 2013-03-13 CN disclosed
WO-2011151683-A1 ZN (II) BASED COLORIMETRIC SENSOR AND PROCESS FOR THE PREPARATION THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2011-12-08 WO disclosed
US-20020094537-A1 Device and method for tracking conditions in an assay PICOLITER INC. 2002-07-18 US disclosed
WO-2002053777-A2 DEVICE AND METHOD FOR TRACKING CONDITIONS IN AN ASSAY PICOLITER INC. (US) 2002-07-11 WO disclosed
EP-0654093-B1 DETECTING AND AMPLIFYING TARGET NUCLEIC ACIDS USING EXONUCLEOLYTIC ACTIVITY ABBOTT LAB (US) 2001-01-03 EP disclosed
EP-0654093-A4 DETECTING AND AMPLIFYING TARGET NUCLEIC ACIDS USING EXONUCLEOLYTIC ACTIVITY. ABBOTT LAB (US) 1998-01-07 EP disclosed
US-5573907-A Detecting and amplifying target nucleic acids using exonucleolytic activity ABBOTT LABORATORIES (US) 1996-11-12 US disclosed
EP-0654093-A1 DETECTING AND AMPLIFYING TARGET NUCLEIC ACIDS USING EXONUCLEOLYTIC ACTIVITY ABBOTT LABORATORIES (US) 1995-05-24 EP disclosed
WO-1994003636-A1 DETECTING AND AMPLIFYING TARGET NUCLEIC ACIDS USING EXONUCLEOLYTIC ACTIVITY ABBOTT LABORATORIES (US) 1994-02-17 WO disclosed