SCHEMBL7720754

SCHEMBL7720754

CCC(=O)Oc1ccc(S(=O)(=O)C(=[N+]=[N-])C(=O)C(C)(C)C)cc1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
ESR1 P03372 2/20 0.42
HIF1A Q16665 2/20 0.42
RECQL P46063 1/20 0.42
ELANE P08246 9/20 0.41
PRTN3 P24158 4/20 0.37
MAPT P10636 3/20 0.35
POLB P06746 1/20 0.35
PKM P14618 1/20 0.35
ACHE P22303 1/20 0.35
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
LMNA P02545 1/20 0.34
NFKB1 P19838 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7717471 0.85 MAPT (0.51) KMT2ASMN1; SMN2ELANEPRTN3MAPT
SCHEMBL7717475 0.85 KMT2A (0.45) KMT2ASMN1; SMN2ESR1HIF1ARECQL
SCHEMBL7696164 0.83 MMP2 (0.42) KMT2ASMN1; SMN2RECQLELANEMAPT
SCHEMBL7722363 0.82 ELANE (0.43) SMN1; SMN2ELANEPRTN3MAPTPOLB
SCHEMBL7721776 0.81 KMT2A (0.43) KMT2ASMN1; SMN2ESR1HIF1ARECQL
SCHEMBL7722379 0.81 KMT2A (0.43) KMT2ASMN1; SMN2ESR1HIF1ARECQL
SCHEMBL7722372 0.81 KMT2A (0.49) KMT2ASMN1; SMN2ESR1HIF1ARECQL
SCHEMBL7717473 0.81 KMT2A (0.43) KMT2ASMN1; SMN2ESR1HIF1ARECQL
SCHEMBL7692516 0.80 MMP2 (0.39) KMT2ASMN1; SMN2RECQLELANEMAPT
SCHEMBL7721805 0.80 ELANE (0.53) KMT2ASMN1; SMN2ESR1HIF1ARECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6395446-B1 CONTAINING SULFONYLDIAZOMETHANE COMPOUND AS ACID GENERATOR SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-05-28 US disclosed