Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7722379 | 0.89 | KMT2A (0.43) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL7722368 | 0.87 | KMT2A (0.49) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL7721785 | 0.87 | MAPT (0.44) | KMT2AESR1ELANEMAPTCYP11B1 | |
| SCHEMBL7721805 | 0.86 | ELANE (0.53) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL7690054 | 0.85 | MMP2 (0.40) | KMT2ASMN1; SMN2RAB9ACYP11B1CYP11B2 | |
| SCHEMBL7720748 | 0.85 | KMT2A (0.41) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL7720726 | 0.84 | ELANE (0.44) | SMN1; SMN2ELANEMAPTCYP11B1CYP11B2 | |
| SCHEMBL7695885 | 0.83 | MMP2 (0.37) | KMT2ASMN1; SMN2ELANERAB9ACYP11B1 | |
| SCHEMBL6742537 | 0.82 | TSHR (0.46) | — | |
| SCHEMBL7720754 | 0.81 | KMT2A (0.42) | KMT2ASMN1; SMN2ESR1HIF1ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395446-B1 | CONTAINING SULFONYLDIAZOMETHANE COMPOUND AS ACID GENERATOR | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-05-28 | — | — | US | disclosed |