Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 1/20 | 0.76 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5702540 | 0.90 | TSPO (0.81) | TSPOTP53MAPT | |
| SCHEMBL8959235 | 0.89 | TSPO (0.71) | TSPOTP53MAPTPOLB | |
| SCHEMBL5702522 | 0.88 | TSPO (0.74) | TSPOTP53MAPT | |
| SCHEMBL197375 | 0.86 | TSPO (1.00) | TSPOMAPT | |
| SCHEMBL7496839 | 0.85 | TSPO (0.82) | TSPOTP53MAPTPOLB | |
| SCHEMBL6256479 | 0.83 | TSPO (0.71) | TSPOMAPTPOLB | |
| SCHEMBL8959261 | 0.83 | TSPO (0.83) | TSPOMAPT | |
| SCHEMBL7750398 | 0.82 | TSPO (0.69) | TSPO | |
| SCHEMBL14300517 | 0.82 | TSPO (0.80) | TSPOMAPT | |
| SCHEMBL5702800 | 0.81 | TSPO (0.68) | TSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395729-B1 | CENTRAL NERVOUS SYSTEM DISORDERS | SANOFI-SYNTHELABO (FR) | 2002-05-28 | — | — | US | disclosed |
| US-6262045-B1 | TREATMENT OF ANXIETY; SLEEP DISORDER; EPILEPSY; SPASTICITY; MUSCLE CONTRACTURE OR AN EXTRAPYRAMIDAL SYNDROM; INDUCING OR MAINTAINING ANAESTHESIA | SANOFI-SYNTHELABO (FR) | 2001-07-17 | — | — | US | disclosed |