Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 13/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 13/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 10/20 | 0.50 |
| ▸ | RORC | P51449 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5722096 | 0.89 | OPRM1 (0.61) | OPRM1OPRK1OPRD1RORCHDAC1 | |
| SCHEMBL7760721 | 0.84 | EPHX1 (0.52) | RORCNPC1RAB9AHDAC1HDAC6 | |
| SCHEMBL30093246 | 0.82 | OPRM1 (0.57) | OPRM1OPRK1OPRD1RORCHDAC1 | |
| SCHEMBL23825801 | 0.81 | RORC (0.49) | OPRM1OPRK1OPRD1RORCHDAC1 | |
| SCHEMBL23825798 | 0.81 | RORC (0.49) | OPRM1OPRK1OPRD1RORCHDAC1 | |
| SCHEMBL12126132 | 0.80 | OPRM1 (0.54) | OPRM1OPRK1OPRD1RORCKDM4E | |
| SCHEMBL5519308 | 0.79 | KDM4E (0.54) | OPRM1OPRK1OPRD1RORCHDAC1 | |
| SCHEMBL8313794 | 0.79 | OPRM1 (0.51) | OPRM1OPRK1OPRD1RORCHDAC1 | |
| SCHEMBL5519302 | 0.79 | KDM4E (0.54) | OPRM1OPRK1OPRD1RORCHDAC1 | |
| SCHEMBL8313789 | 0.79 | OPRM1 (0.51) | OPRM1OPRK1OPRD1RORCHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6387949-B1 | ANALGESICS | ASTRAZENECA CANADA INC. (CA) | 2002-05-14 | — | — | US | disclosed |