Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ACE | P12821 | 4/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6907074 | 0.86 | PPARG (0.49) | SMN1; SMN2ACEMEN1HTTKMT2A | |
| SCHEMBL4224537 | 0.85 | SMN1; SMN2 (0.49) | SMN1; SMN2ACEMMP8MAPTMEN1 | |
| SCHEMBL7722450 | 0.84 | SMN1; SMN2 (0.48) | SMN1; SMN2ACEMMP8MAPTMEN1 | |
| SCHEMBL5674353 | 0.82 | SMN1; SMN2 (0.46) | SMN1; SMN2ACEMMP8MAPTHTT | |
| SCHEMBL9773201 | 0.82 | SMN1; SMN2 (0.46) | SMN1; SMN2ACEMMP8MAPTHTT | |
| SCHEMBL1858577 | 0.82 | SMN1; SMN2 (0.46) | SMN1; SMN2ACEMMP8MAPTHTT | |
| SCHEMBL6632835 | 0.79 | SMN1; SMN2 (0.54) | SMN1; SMN2ACEMMP8MAPTMEN1 | |
| SCHEMBL6632836 | 0.79 | SMN1; SMN2 (0.54) | SMN1; SMN2ACEMMP8MAPTMEN1 | |
| SCHEMBL13902855 | 0.78 | SMN1; SMN2 (0.44) | SMN1; SMN2ACEMMP8MAPTMEN1 | |
| SCHEMBL20676110 | 0.77 | SMN1; SMN2 (0.52) | SMN1; SMN2ACEMMP8MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395918-B1 | Conversion of a hydroxy group in certain alcohols into a fluorosulfonate ester or a trifluoromethylsulfonate ester | LOEWENTHAL HANS JACOB EDGAR (IL) | 2002-05-28 | — | — | US | disclosed |