Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | ACE | P12821 | 3/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6507266 | 0.83 | KMT2A (0.47) | SMN1; SMN2ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL5080014 | 0.83 | KMT2A (0.47) | SMN1; SMN2ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL7441323 | 0.80 | LMNA (0.51) | CA1CA2ALDH1A1LMNAPLAU | |
| SCHEMBL4224537 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2MMP8ACEMEN1MAPT | |
| SCHEMBL9618581 | 0.79 | LMNA (0.43) | SMN1; SMN2TSHRALDH1A1ACELMNA | |
| SCHEMBL7721713 | 0.78 | SMN1; SMN2 (0.49) | SMN1; SMN2TSHRMMP8ACELMNA | |
| SCHEMBL7722450 | 0.78 | SMN1; SMN2 (0.48) | SMN1; SMN2MMP8ACELMNAMEN1 | |
| SCHEMBL605143 | 0.77 | ALDH1A1 (0.51) | CA12CA9ALDH1A1LMNAPLAU | |
| SCHEMBL4142757 | 0.76 | CYP24A1 (0.49) | TSHRALDH1A1LMNAUSP2MAPT | |
| SCHEMBL1858577 | 0.76 | SMN1; SMN2 (0.46) | SMN1; SMN2MMP8ACEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1891014-B1 | IMPROVED PROCESS FOR CRYSTALLIZATION OF BENAZEPRIL HYDROCHLORIDE | LUPIN LTD (IN) | 2009-03-11 | — | — | EP | disclosed |