Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 3/20 | 0.37 |
| ▸ | PTPN5 | P54829 | 4/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9135944 | 0.82 | FEN1 (0.41) | FEN1PTPN5PTPN2PTGDR2ALOX5AP | |
| SCHEMBL11163642 | 0.80 | GABRA1 (0.55) | FEN1PTPN5PTPN2ALOX5APHTR1A | |
| SCHEMBL15253060 | 0.80 | FEN1 (0.40) | FEN1PTPN5PTPN2PTGDR2ALOX5AP | |
| SCHEMBL7721762 | 0.78 | HDAC4 (0.37) | CYP1A2GABRA1GABRB2HIF1AKMT2A | |
| SCHEMBL4958862 | 0.77 | PTPN5 (0.46) | FEN1PTPN5PTPN2PTGDR2ALOX5AP | |
| SCHEMBL4958978 | 0.77 | PTPN5 (0.46) | FEN1PTPN5PTPN2PTGDR2ALOX5AP | |
| SCHEMBL201425 | 0.77 | PTPN5 (0.46) | FEN1PTPN5PTPN2PTGDR2ALOX5AP | |
| SCHEMBL4960398 | 0.77 | PTPN5 (0.46) | FEN1PTPN5PTPN2PTGDR2ALOX5AP | |
| SCHEMBL4959318 | 0.77 | PTPN5 (0.46) | FEN1PTPN5PTPN2PTGDR2ALOX5AP | |
| SCHEMBL4618238 | 0.76 | PTGDR2 (0.41) | FEN1PTPN5PTPN2PTGDR2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6388044-B1 | THERMOSETTING POLYETHER; CROSSLINKING BY HEATING | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-05-14 | — | — | US | disclosed |