Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 6/20 | 0.32 |
| ▸ | CNR2 | P34972 | 5/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | PPIA | P62937 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | KMO | O15229 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9244494 | 0.82 | HDAC4 (0.42) | HDAC4HDAC2HDAC8ALDH1A1ALOX15 | |
| SCHEMBL5275279 | 0.79 | HDAC4 (0.38) | HDAC4HDAC2HDAC8ALDH1A1ALOX15 | |
| SCHEMBL7721763 | 0.78 | FEN1 (0.37) | HDAC4HDAC2HDAC8GABRA1GABRB2 | |
| SCHEMBL2530090 | 0.78 | HDAC4 (0.39) | HDAC4HDAC2HDAC8ALDH1A1ALOX15 | |
| SCHEMBL7531576 | 0.77 | HDAC4 (0.50) | HDAC4HDAC2HDAC8ALDH1A1ALOX15 | |
| SCHEMBL6004412 | 0.77 | HDAC4 (0.50) | HDAC4HDAC2HDAC8ALDH1A1ALOX15 | |
| SCHEMBL3169205 | 0.75 | HDAC4 (0.52) | HDAC4HDAC2HDAC8ALDH1A1ALOX15 | |
| SCHEMBL27584477 | 0.74 | HPGD (0.37) | HDAC4HDAC2HDAC8KMOKMT2A | |
| Water SCHEMBL27641338 | 0.73 | HDAC4 (0.50) | HDAC4HDAC2HDAC8ALDH1A1ALOX15 | |
| SCHEMBL7869684 | 0.73 | TRPA1 (0.48) | HDAC4HDAC2HDAC8ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6388044-B1 | THERMOSETTING POLYETHER; CROSSLINKING BY HEATING | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-05-14 | — | — | US | disclosed |