Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14314327 | 0.80 | KDM4E (0.39) | ALDH1A1KDM4EMAPTTP53GAA | |
| SCHEMBL7720635 | 0.76 | HIF1A (0.41) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL19450271 | 0.75 | MAPT (0.48) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL14316238 | 0.74 | KDM4E (0.31) | ALDH1A1KDM4E | |
| SCHEMBL16365919 | 0.73 | HIF1A (0.34) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL18079242 | 0.73 | MAPT (0.47) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL14297124 | 0.71 | — | — | |
| SCHEMBL7723490 | 0.71 | CYP1A2 (0.33) | MAPTCSNK2A1HTR2CHTR2BHTR2A | |
| SCHEMBL17189711 | 0.70 | ALDH1A1 (0.39) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL15682104 | 0.70 | PDE4D (0.40) | ALDH1A1KDM4EMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1261573-A2 | ASYMMETRIC LIGANDS HAVING USE AS CATALYSTS | 1428388 Ontario Limited (CA) | 2002-12-04 | — | — | EP | claimed |
| WO-2001007386-A2 | ASYMMETRIC LIGANDS HAVING USE AS CATALYSTS | 1428388 ONTARIO LIMITED (CA) | 2001-02-01 | — | — | WO | claimed |