SCHEMBL77218

SCHEMBL77218

Cc1nc(C)c(C)s1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26115720 0.97
Aminothiazole SCHEMBL5976750 0.74 NOS1 (0.56)
SCHEMBL10022977 0.73 NOS1 (0.52)
SCHEMBL12537263 0.73 COMT (0.52)
Styrene SCHEMBL28202548 0.73 ALDH1A1 (0.50)
SCHEMBL102273 0.71
SCHEMBL160277 0.69
SCHEMBL361464 0.69
SCHEMBL12159328 0.69
SCHEMBL2745154 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2514 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260096574-A1 CHOCOLATE REPLICAS PRODUCED FROM INDIVIDUAL COMPONENTS VOYAGE FOODS INC (US) 2026-04-09 US claimed
US-12568998-B2 Flavouring composition with balanced taste profile SYMRISE AG (DE) 2026-03-10 US claimed
US-20260007144-A1 CHOCOLATE REPLICAS PRODUCED FROM INDIVIDUAL COMPONENTS VOYAGE FOODS INC (US) 2026-01-08 US claimed
US-12493040-B2 Cancer detection method using sense of smell of nematode HIROTSU BIO SCIENCE INC. (JP) 2025-12-09 US claimed
EP-3766492-B1 THIAZOLINE AND THIAZOLE COMPOUNDS FOR USE IN THE PROPHYLAXIS OR TREATMENT OF HYPOXIC INJURY OR ISCHEMIA-REPERFUSION INJURY SCENT SCIENCE INT INC (JP) 2025-10-15 EP claimed
EP-4444108-B1 ALDEHYDE MIXTURES FOR FLAVOUR IMPROVEMENT SYMRISE AG (DE) 2025-09-10 EP claimed
EP-4606226-A2 CHOCOLATE REPLICAS PRODUCED FROM INDIVIDUAL COMPONENTS Voyage Foods, Inc. (US) 2025-08-27 EP claimed
WO-2025149550-A1 PROCESS GIVAUDAN SA (CH) 2025-07-17 WO claimed
EP-4585052-A1 OIL/FAT SENSATION ENHANCING AGENT AJINOMOTO CO., INC. (JP) 2025-07-16 EP claimed
EP-4585053-A1 PROCESS FOR PREPARING A FLAVOUR COMPOSITION Givaudan SA (CH) 2025-07-16 EP claimed
CN-1426303-A Thiazole, imidazole and oxazole compounds and treatment of diseases associated with protein aging ALTEON INC (US) 2003-06-25 CN claimed
US-20020183317-A1 Method for treating fibrotic diseases or other indications IIC SYNVISTA THERAPEUTICS, INC. 2002-12-05 US claimed
EP-1248615-A1 THIAZOLE, IMIDAZOLE AND OXAZOLE COMPOUNDS AND TREATMENTS OF DISORDERS ASSOCIATED WITH PROTEIN AGING Alteon, Inc. (US) 2002-10-16 EP claimed
US-20020119970-A1 Method for treating glaucoma IIB SYNVISTA THERAPEUTICS, INC. 2002-08-29 US claimed
WO-2002053156-A1 METHOD FOR TREATING GLAUCOMA II B ALTEON, INC. (US) 2002-07-11 WO claimed
WO-2002053161-A1 METHOD FOR TREATING FIBROTIC DISEASES OR OTHER INDICATIONS ALTEON, INC. (US) 2002-07-11 WO claimed
US-20020022622-A1 Thiazole, imidazole and oxazole compounds and treatments of disorders associated with protein aging SYNVISTA THERAPEUTICS, INC. 2002-02-21 US claimed
WO-2001052847-A1 THIAZOLE, IMIDAZOLE AND OXAZOLE COMPOUNDS AND TREATMENTS OF DISORDERS ASSOCIATED WITH PROTEIN AGING ALTEON, INC. (US) 2001-07-26 WO claimed
US-RE29843-E Substituted thiazoles and flavoring processes and products produced thereby INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1978-11-21 US claimed
US-4093752-A FOODSTUFFS, CHEWING GUM, TOOTHPASTE, MEDICINES INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1978-06-06 US claimed