Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.58 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.58 |
| ▸ | F2 | P00734 | 4/20 | 0.51 |
| ▸ | F10 | P00742 | 4/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | CTSG | P08311 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9435428 | 0.90 | ITGB3 (0.60) | ITGB3ITGA2BCTSGCMA1HDAC1 | |
| SCHEMBL8776989 | 0.88 | F2 (0.49) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL7387875 | 0.86 | ITGB3 (0.76) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL7438806 | 0.83 | ITGB3 (0.71) | ITGB3ITGA2BPRSS1CTSGCMA1 | |
| Acetic Acid SCHEMBL9097876 | 0.82 | ITGB3 (0.68) | ITGB3ITGA2BPRSS1CTSGCMA1 | |
| SCHEMBL9710588 | 0.82 | ITGB3 (0.64) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL7390380 | 0.82 | ITGB3 (0.64) | ITGB3ITGA2BF2F10PRSS1 | |
| Hydrochloric Acid SCHEMBL9435247 | 0.82 | ITGB3 (0.70) | ITGB3ITGA2BPRSS1CTSGCMA1 | |
| SCHEMBL9103107 | 0.82 | ITGB3 (0.70) | ITGB3ITGA2BPRSS1CTSGCMA1 | |
| SCHEMBL7386054 | 0.81 | ITGB3 (0.76) | ITGB3ITGA2BF2F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574545-B1 | PHENYL AMIDINES DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 1994-11-30 | — | — | EP | claimed |
| US-6387880-B1 | MIXTURE OF DRUG AND SOLVENT | G.D. SEARLE & CO. | 2002-05-14 | — | — | US | disclosed |
| EP-0729362-B1 | TRANSDERMAL COMPOSITION OF N- N- 5- 4-(AMINOIMINOMETHYL)PHENYL]-1-OXOPENTYL]-L-alpha-ASPARTYL]-L-PHENYLALANINE OR ITS ESTERS AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS | SEARLE & CO (US) | 2000-01-12 | — | — | EP | disclosed |
| EP-0729362-A1 | TRANSDERMAL COMPOSITION OF N- N- 5- 4-(AMINOIMINOMETHYL)PHENYL]-1-OXOPENTYL]-L-$g(a)-ASPARTYL]-L-PHENYLALANINE OR ITS ESTERS AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS | G.D. SEARLE & CO. (US) | 1996-09-04 | — | — | EP | disclosed |
| WO-1995013825-A1 | TRANSDERMAL COMPOSITION OF N-[N-[5-[4-(AMINOIMINOMETHYL)PHENYL]-1-OXOPENTYL]-L-α-ASPARTYL]-L-PHENYLALANINE OR ITS ESTERS AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS | G.D. SEARLE & CO. (US) | 1995-05-26 | — | — | WO | disclosed |