Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11804667 | 0.85 | TDP1 (0.40) | TDP1MEN1LMNATHRBBLM | |
| SCHEMBL548692 | 0.80 | MEN1 (0.46) | TDP1MEN1LMNATHRBBLM | |
| SCHEMBL604701 | 0.74 | ALDH1A1 (0.41) | TDP1MEN1LMNATHRBBLM | |
| SCHEMBL548457 | 0.69 | TDP1 (0.50) | TDP1MEN1LMNATHRBBLM | |
| SCHEMBL547605 | 0.69 | CYP3A4 (0.35) | TDP1ERN1KDM4EALDH1A1 | |
| SCHEMBL604700 | 0.69 | ERN1 (0.39) | TDP1MEN1LMNATHRBBLM | |
| SCHEMBL547875 | 0.68 | MEN1 (0.41) | TDP1MEN1LMNATHRBBLM | |
| SCHEMBL547850 | 0.67 | ALDH1A1 (0.39) | TDP1MEN1LMNATHRBBLM | |
| SCHEMBL9797598 | 0.67 | TDP1 (0.35) | TDP1MEN1LMNATHRBBLM | |
| SCHEMBL11183863 | 0.67 | MEN1 (0.39) | TDP1MEN1LMNATHRBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230400-A1 | DEGRADATION OF POLYCYCLIC AROMATIC HYDROCARBONS | University of Utah Research Foundation (US) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001032936-A1 | DEGRADATION OF POLYCYCLIC AROMATIC HYDROCARBONS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2001-05-10 | — | — | WO | disclosed |