Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8196191 | 0.71 | KEAP1 (0.33) | ALDH1A1 | |
| SCHEMBL11316747 | 0.68 | ALDH1A1 (0.38) | SMN1; SMN2MEN1ALDH1A1LMNAALOX12 | |
| SCHEMBL11316752 | 0.68 | ALDH1A1 (0.38) | SMN1; SMN2MEN1ALDH1A1LMNAALOX12 | |
| SCHEMBL11325531 | 0.68 | EPHX1 (0.43) | EPHX1PDK1PDK2PDK3PDK4 | |
| SCHEMBL11325529 | 0.68 | EPHX1 (0.43) | EPHX1PDK1PDK2PDK3PDK4 | |
| SCHEMBL7722073 | 0.67 | MEN1 (0.36) | SMN1; SMN2MEN1ALDH1A1LMNAALOX12 | |
| SCHEMBL9067197 | 0.66 | ALDH1A1 (0.35) | EPHX1ALDH1A1 | |
| SCHEMBL25460834 | 0.65 | EPHX1 (0.40) | HDAC8HDAC6EPHX1PDK1PDK2 | |
| SCHEMBL11670727 | 0.65 | HDAC8 (0.38) | HDAC8HDAC6EPHX1PDK1PDK2 | |
| SCHEMBL11528167 | 0.64 | EPHX1 (0.31) | EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395849-B1 | RADICAL INITIATORS AND NEUTRALIZATION | NITTO BOSEKI CO., LTD. (JP) | 2002-05-28 | — | — | US | disclosed |