Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 13/20 | 0.38 |
| ▸ | ANPEP | P15144 | 6/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7722109 | 1.00 | BTK (0.38) | BTKMMP2ANPEPCTSKCA1 | |
| SCHEMBL7727788 | 0.90 | BTK (0.44) | BTKMMP2ANPEPCTSKCA1 | |
| SCHEMBL7727791 | 0.90 | BTK (0.44) | BTKMMP2ANPEPCTSKCA1 | |
| SCHEMBL3103450 | 0.84 | MMP2 (0.61) | MMP2ANPEP | |
| SCHEMBL2404149 | 0.84 | MMP2 (0.61) | MMP2ANPEP | |
| SCHEMBL7731141 | 0.84 | ALDH1A1 (0.43) | MMP2ANPEPKMT2AALDH1A1 | |
| SCHEMBL7731145 | 0.84 | ALDH1A1 (0.43) | MMP2ANPEPKMT2AALDH1A1 | |
| SCHEMBL14467624 | 0.83 | MMP2 (0.45) | MMP2ANPEPKMT2AL3MBTL1 | |
| SCHEMBL7722292 | 0.83 | ANPEP (0.52) | MMP2ANPEPALDH1A1 | |
| SCHEMBL7722294 | 0.83 | ANPEP (0.52) | MMP2ANPEPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399629-B1 | PYRROLIDINES AND PIPERIDINES FOR TREATING MICROBIAL INFECTIONS BY REDUCING EXPORT OF COADMINISTERED ANTIMICROBIAL AGENT OR COMPOUND SYNTHESIZED BY MICROBES FOR THEIR GROWTH; REDUCING IN VIVO AVAILABILITY | MICROCIDE PHARMACEUTICALS, INC. | 2002-06-04 | — | — | US | disclosed |
| WO-2000001714-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 2000-01-13 | — | — | WO | disclosed |