Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 2/20 | 0.50 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.49 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.49 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | GLS | O94925 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6635582 | 0.89 | NPFFR1 (0.52) | NAMPTTLR7NPFFR1NPFFR2KMT2A | |
| SCHEMBL8693590 | 0.87 | CA1 (0.54) | CYP17A1NAMPTTLR7KMT2APTPN11 | |
| SCHEMBL10249437 | 0.86 | CYP17A1 (0.68) | CYP17A1NAMPTPPARAPPARGSLC1A3 | |
| SCHEMBL7043590 | 0.85 | LTA4H (0.62) | KMT2ANPC1RAB9A | |
| SCHEMBL3218237 | 0.85 | CA1 (0.48) | CYP17A1NAMPTTLR7NPFFR1NPFFR2 | |
| SCHEMBL23099689 | 0.84 | KMT2A (0.51) | NAMPTTLR7NPFFR1NPFFR2PPARA | |
| SCHEMBL15295619 | 0.83 | NAMPT (0.49) | CYP17A1NAMPTTLR7PTPN11NPC1 | |
| SCHEMBL30483102 | 0.83 | CA1 (0.46) | CYP17A1NAMPTTLR7NPFFR1NPFFR2 | |
| SCHEMBL17874907 | 0.83 | HPGD (0.50) | CYP17A1NAMPTTLR7PTPN11NPC1 | |
| SCHEMBL669133 | 0.82 | PTPN11 (0.49) | KMT2APTPN11RAB9APOLBCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399629-B1 | PYRROLIDINES AND PIPERIDINES FOR TREATING MICROBIAL INFECTIONS BY REDUCING EXPORT OF COADMINISTERED ANTIMICROBIAL AGENT OR COMPOUND SYNTHESIZED BY MICROBES FOR THEIR GROWTH; REDUCING IN VIVO AVAILABILITY | MICROCIDE PHARMACEUTICALS, INC. | 2002-06-04 | — | — | US | disclosed |