Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.75 |
| ▸ | MAPT | P10636 | 10/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | RORC | P51449 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7726215 | 0.93 | NPSR1 (0.86) | NPSR1MAPTKDM4ELMNAMEN1 | |
| SCHEMBL7722815 | 0.86 | NPSR1 (1.00) | NPSR1MAPTKDM4ELMNAMEN1 | |
| SCHEMBL7723463 | 0.83 | NPSR1 (0.71) | NPSR1MAPTKDM4ELMNAMEN1 | |
| SCHEMBL7723460 | 0.82 | NPSR1 (0.70) | NPSR1MAPTKDM4ELMNAMEN1 | |
| SCHEMBL30879656 | 0.81 | KDM4E (0.56) | NPSR1MAPTKDM4ELMNAMEN1 | |
| SCHEMBL13539146 | 0.81 | KDM4E (0.56) | NPSR1MAPTKDM4ELMNAMEN1 | |
| SCHEMBL1611235 | 0.79 | KDM4E (0.52) | NPSR1MAPTKDM4ELMNAMEN1 | |
| SCHEMBL6226561 | 0.77 | MAPT (0.74) | NPSR1MAPTKDM4ELMNAMEN1 | |
| SCHEMBL16099170 | 0.75 | NPSR1 (0.60) | NPSR1MAPTKDM4ELMNAMEN1 | |
| SCHEMBL28267725 | 0.75 | KDM4E (0.63) | MAPTKDM4ELMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399631-B1 | 3-AMIDO OR 3-SULFONAMIDO; EATING DISORDERS IN HUMANS, DOGS AND CATS | PFIZER INC. | 2002-06-04 | — | — | US | disclosed |