Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.56 |
| ▸ | HPGD | P15428 | 5/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | RORC | P51449 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13539146 | 1.00 | KDM4E (0.56) | KDM4EHPGDHTTRORCALDH1A1 | |
| SCHEMBL29540056 | 0.92 | KDM4E (0.65) | KDM4EHPGDHTTALDH1A1MAPT | |
| SCHEMBL153044 | 0.92 | KDM4E (0.65) | KDM4EHPGDHTTALDH1A1MAPT | |
| SCHEMBL13236634 | 0.90 | KDM4E (0.52) | KDM4EHPGDHTTRORCALDH1A1 | |
| SCHEMBL28267725 | 0.88 | KDM4E (0.63) | KDM4EHPGDHTTRORCALDH1A1 | |
| SCHEMBL30439266 | 0.86 | KDM4E (0.50) | KDM4EHPGDHTTRORCALDH1A1 | |
| SCHEMBL2735111 | 0.86 | KDM4E (0.58) | KDM4EHPGDHTTALDH1A1MAPT | |
| SCHEMBL5662028 | 0.84 | HPGD (0.72) | KDM4EHPGDHTTRORCALDH1A1 | |
| SCHEMBL5797538 | 0.84 | MAPT (0.55) | KDM4EHPGDHTTRORCALDH1A1 | |
| SCHEMBL27900930 | 0.83 | KDM4E (0.55) | KDM4EHPGDHTTALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240142379-A1 | METHODS AND SYSTEMS FOR IMAGING REACTION PRODUCTS | CORNELL UNIVERSITY | 2024-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240142379-A1 | METHODS AND SYSTEMS FOR IMAGING REACTION PRODUCTS | AGER, FGB, PFAS | KDM4E 4444/4885HPGD 1821/4885HTT 1138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.