Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | RORC | P51449 | 3/20 | 0.53 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7726215 | 0.90 | NPSR1 (0.86) | NPSR1MAPTKDM4ELMNAMEN1 | |
| SCHEMBL1593294 | 0.85 | NPY5R (0.74) | NPSR1MAPTKDM4ELMNAMEN1 | |
| SCHEMBL7722764 | 0.83 | NPSR1 (0.75) | NPSR1MAPTKDM4ELMNAMEN1 | |
| SCHEMBL7722815 | 0.83 | NPSR1 (1.00) | NPSR1MAPTKDM4ELMNAMEN1 | |
| SCHEMBL5163862 | 0.82 | KDM4E (0.64) | NPSR1MAPTKDM4ELMNAMEN1 | |
| SCHEMBL7723460 | 0.80 | NPSR1 (0.70) | NPSR1MAPTKDM4ELMNAMEN1 | |
| SCHEMBL4849333 | 0.75 | KDM4E (0.67) | NPSR1MAPTKDM4ELMNAMEN1 | |
| SCHEMBL5794680 | 0.75 | KDM4E (0.55) | MAPTKDM4ELMNAMEN1KMT2A | |
| SCHEMBL5797737 | 0.74 | KDM4E (0.54) | MAPTKDM4ELMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL5798005 | 0.74 | PTGER4 (0.57) | MAPTKDM4ELMNAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399631-B1 | 3-AMIDO OR 3-SULFONAMIDO; EATING DISORDERS IN HUMANS, DOGS AND CATS | PFIZER INC. | 2002-06-04 | — | — | US | disclosed |