Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LATS1 | O95835 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28931135 | 0.96 | CYP2C19 (0.40) | MAPTCYP2C19CYP3A4ALDH1A1L3MBTL1 | |
| SCHEMBL1351011 | 0.80 | LATS1 (0.37) | CYP2C19CYP3A4ALDH1A1MEN1KMT2A | |
| SCHEMBL8950840 | 0.80 | SMN1; SMN2 (0.40) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL27570845 | 0.79 | SMN1; SMN2 (0.38) | ALDH1A1MEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL10890944 | 0.78 | MAPT (0.38) | MAPTCYP2C19CYP3A4ALDH1A1L3MBTL1 | |
| Bromide SCHEMBL9334755 | 0.78 | MAPT (0.35) | MAPTCYP2C19CYP3A4ALDH1A1L3MBTL1 | |
| SCHEMBL8915997 | 0.78 | MAPT (0.36) | MAPTALDH1A1L3MBTL1NPSR1CTSL | |
| SCHEMBL19442305 | 0.77 | MGAM (0.39) | ALDH1A1MEN1KMT2ASMN1; SMN2MGAM | |
| SCHEMBL6840056 | 0.77 | SPHK1 (0.44) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL9335877 | 0.77 | CTSD (0.34) | MAPTCYP2C19CYP3A4ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399809-B1 | FROM MALONIC ACID MONOESTER AMIDE | DEGUSSA AG (DE) | 2002-06-04 | — | — | US | disclosed |