Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LATS1 | O95835 | 1/20 | 0.32 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.32 |
| ▸ | METAP1 | P53582 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL9335839 | 0.98 | CTSD (0.34) | CTSDMAPTPLAUPLATMETAP2 | |
| SCHEMBL9335864 | 0.90 | METAP2 (0.37) | CTSDMAPTPLAUPLATMETAP2 | |
| SCHEMBL9335858 | 0.90 | METAP2 (0.37) | CTSDMAPTPLAUPLATMETAP2 | |
| SCHEMBL9337920 | 0.89 | METAP2 (0.39) | CTSDMAPTPLAUPLATMETAP2 | |
| SCHEMBL9334309 | 0.86 | TERT (0.34) | CTSDMAPTPLAUPLAT | |
| SCHEMBL9334251 | 0.80 | DPP4 (0.40) | CTSDMAPTPLAUPLATKMT2A | |
| SCHEMBL12864489 | 0.80 | MGAM (0.34) | CTSDSMN1; SMN2ALDH1A1LATS1MEN1 | |
| SCHEMBL9334619 | 0.80 | CTSD (0.37) | CTSDMETAP2SMN1; SMN2METAP1ALOX15 | |
| Citric Acid SCHEMBL9338239 | 0.80 | ALDH1A1 (0.34) | CTSDMAPTMETAP2ALDH1A1METAP1 | |
| Hydrochloric Acid SCHEMBL9334275 | 0.79 | DPP4 (0.39) | MAPTPLAUPLATKMT2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0249434-B1 | Peptide derivatives and processes for their preparation | VYZK USTAV FARM BIOCHEM SP (CZ) | 1994-05-04 | — | — | EP | disclosed |
| US-4898930-A | Peptide derivatives and processes for their preparation | SPOFA, SPOJENE PODNIKY PRO (CS) | 1990-02-06 | — | — | US | disclosed |
| EP-0249434-A2 | Peptide derivatives and processes for their preparation | Vyzkumny ustav pro farmacii a biochemii (CZ) | 1987-12-16 | — | — | EP | disclosed |