Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 2/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7732500 | 0.97 | HDAC3 (0.33) | HDAC3HDAC1HDAC2PPARAPPARD | |
| SCHEMBL7735446 | 0.92 | PPARD (0.32) | HDAC3HDAC1HDAC2PPARAPPARD | |
| SCHEMBL7722892 | 0.92 | PTGS2 (0.38) | PTGS2S1PR1PPARAPPARG | |
| SCHEMBL7734772 | 0.91 | HTR2A (0.37) | HDAC3HDAC1HDAC2PTGS2THRB | |
| SCHEMBL7730819 | 0.90 | THRB (0.33) | PTGS2THRBS1PR1PPARAPPARD | |
| SCHEMBL7732528 | 0.90 | HTR2A (0.36) | HDAC3HDAC1HDAC2PTGS2THRB | |
| SCHEMBL7729257 | 0.90 | THRB (0.33) | HDAC3HDAC1HDAC2PTGS2THRB | |
| SCHEMBL7729601 | 0.90 | THRB (0.38) | PTGS2THRBS1PR1PPARAFFAR4 | |
| SCHEMBL7722830 | 0.88 | THRB (0.40) | PTGS2THRBS1PR1PPARAPPARG | |
| SCHEMBL7729958 | 0.88 | HTR2A (0.39) | PTGS2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |