Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 20/20 | 0.67 |
| ▸ | RXRG | P48443 | 18/20 | 0.67 |
| ▸ | RARB | P10826 | 5/20 | 0.67 |
| ▸ | RARG | P13631 | 5/20 | 0.67 |
| ▸ | RARA | P10276 | 4/20 | 0.67 |
| ▸ | RXRB | P28702 | 13/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7722935 | 1.00 | RXRA (0.67) | RXRARXRGRARBRARGRARA | |
| SCHEMBL8015878 | 0.86 | RXRA (0.51) | RXRARXRGRARBRARGRARA | |
| SCHEMBL7723065 | 0.81 | RXRA (1.00) | RXRARXRGRARBRARGRARA | |
| SCHEMBL7723063 | 0.81 | RXRA (1.00) | RXRARXRGRARBRARGRARA | |
| SCHEMBL7732095 | 0.76 | RXRA (1.00) | RXRARXRGRARBRARGRARA | |
| SCHEMBL7732097 | 0.76 | RXRA (1.00) | RXRARXRGRARBRARGRARA | |
| SCHEMBL7731726 | 0.76 | RXRA (1.00) | RXRARXRGRARBRARGRARA | |
| SCHEMBL7731728 | 0.76 | RXRA (1.00) | RXRARXRGRARBRARGRARA | |
| SCHEMBL8520386 | 0.73 | RXRA (0.34) | RXRARXRGRARBRARGRARA | |
| SCHEMBL7723117 | 0.70 | RXRA (1.00) | RXRARXRGRARBRARGRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403638-B1 | COMPOUND FOR USE IN TREATING SKIN DISEASES AND DISORDERS, AND FOR TREATING HYPERVITAMINOSIS A SYNDROME | ALLERGAN SALES, INC. | 2002-06-11 | — | — | US | disclosed |