Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.34 |
| ▸ | RXRG | P48443 | 2/20 | 0.34 |
| ▸ | RARA | P10276 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8417706 | 0.76 | SLC6A4 (0.38) | SLC6A4SLC6A3SLC6A2CASP1 | |
| SCHEMBL7722936 | 0.73 | RXRA (0.67) | RXRARXRGRARARARBRARG | |
| SCHEMBL7722935 | 0.73 | RXRA (0.67) | RXRARXRGRARARARBRARG | |
| SCHEMBL7996385 | 0.73 | RXRA (0.59) | RXRARXRGRARARARBRARG | |
| SCHEMBL10726430 | 0.71 | NQO1 (0.47) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL3406637 | 0.71 | SLC6A4 (0.47) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL1952022 | 0.70 | ALDH1A1 (0.42) | SLC6A4SLC6A3 | |
| SCHEMBL8443175 | 0.70 | ALDH1A1 (0.41) | RARBSLC6A4SLC6A3SLC6A2 | |
| SCHEMBL19207570 | 0.70 | MAOA (0.54) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL2443315 | 0.68 | KMT2A (0.38) | SLC6A4SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6005007-A | SKIN DISORDERS | LIGAND PHARMACEUTICALS INCORPORATED | 1999-12-21 | — | — | US | disclosed |