Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 8/20 | 0.41 |
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7723145 | 0.79 | MAPT (0.47) | MAPTHPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2774898 | 0.77 | TNF (0.55) | MAPTHPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1278385 | 0.74 | HMGCR (0.54) | MAPTHPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10769689 | 0.74 | HMGCR (0.54) | MAPTHPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL132430 | 0.73 | MAOB (0.39) | MAPTHPGDMEN1KMT2ARAB9A | |
| SCHEMBL6457663 | 0.73 | L3MBTL1 (0.46) | MAPTMEN1KMT2ASMN1; SMN2TP53 | |
| Methane SCHEMBL8586981 | 0.73 | HMGCR (0.52) | MAPTHPGDMEN1KMT2ASMN1; SMN2 | |
| Methane SCHEMBL5017099 | 0.73 | HMGCR (0.52) | MAPTHPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30672844 | 0.72 | SENP7 (0.41) | GAAL3MBTL1 | |
| SCHEMBL29269889 | 0.72 | SENP7 (0.41) | GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263842-A2 | HYPERBRANCHED AMPHIPHILIC POLYMERIC ADDITIVES AND POLYMER COMPOSITIONS WITH INCREASED SURFACE ENERGY | Ciba SC Holding AG (CH) | 2002-12-11 | — | — | EP | disclosed |
| WO-2001058987-A2 | HYPERBRANCHED AMPHIPHILIC POLYMERIC ADDITIVES AND POLYMER COMPOSITIONS WITH INCREASED SURFACE ENERGY | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2001-08-16 | — | — | WO | disclosed |