Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.58 |
| ▸ | ADRA1D | P25100 | 10/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 10/20 | 0.58 |
| ▸ | ADRA1B | P35368 | 10/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7723314 | 1.00 | HTR1A (0.58) | HTR1AADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL7722713 | 0.99 | HTR1A (0.57) | HTR1AADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL7722712 | 0.99 | HTR1A (0.57) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL7853749 | 0.91 | ADRA1D (0.49) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL7722384 | 0.83 | HTR1A (0.73) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL7722387 | 0.83 | HTR1A (0.73) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL10021791 | 0.81 | HTR1A (0.88) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL12013917 | 0.80 | ADRA1D (0.64) | ADRA1DADRA1AADRA1B | |
| Potassium Ion SCHEMBL7860745 | 0.79 | ADRA1D (0.55) | HTR1AADRA1DADRA1AADRA1B | |
| Potassium Ion SCHEMBL7853719 | 0.79 | ADRA1D (0.55) | HTR1AADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395739-B1 | CARDIOVASCUALR DISORDERS; HYPOTENSIVE AGENTS | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-28 | — | — | US | disclosed |
| EP-1090913-A1 | N-PHENYL-N'-PHENYLPROPYLPIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Zeria Pharmaceutical Co., Ltd. (JP) | 2001-04-11 | — | — | EP | disclosed |