Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.40 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.40 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.40 |
| ▸ | KLK7 | P49862 | 2/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7730530 | 0.95 | MAPT (0.38) | MAPTTPSAB1TPSD1TPSG1MMP1 | |
| SCHEMBL7733653 | 0.94 | MAPT (0.40) | MAPTTPSAB1TPSD1TPSG1KLK7 | |
| SCHEMBL7723264 | 0.85 | SCD (0.35) | MAPTMMP1MMP3MMP9CTSK | |
| SCHEMBL7723171 | 0.76 | MAPT (0.56) | MAPTKLK7KLK5SYKCTSK | |
| SCHEMBL10045813 | 0.75 | MAPT (0.67) | MAPTKLK7KLK5L3MBTL1SYK | |
| SCHEMBL7731104 | 0.74 | MAPT (0.39) | MAPTMMP1MMP3MMP9CTSK | |
| SCHEMBL21164376 | 0.73 | MAPT (0.55) | MAPTKLK7KLK5L3MBTL1ANPEP | |
| Hydrochloric Acid SCHEMBL29401089 | 0.73 | MAPT (0.54) | MAPTKLK7KLK5L3MBTL1ANPEP | |
| SCHEMBL8990124 | 0.72 | MAPT (0.49) | MAPTTPSAB1TPSD1TPSG1KLK7 | |
| SCHEMBL7723247 | 0.72 | MAPT (0.38) | MAPTPOLBMMP1MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436980-B1 | TRANSPORT PROTEIN SUPPRESSORS; MICROBIOCIDES | ESSENTIAL THERAPEUTICS, INC. | 2002-08-20 | — | — | US | disclosed |
| US-6204279-B1 | SECONDARY AMIDE CONTAINING BENZOXAZOLE DERIVATIVES | MICROCIDE PHARMACEUTICALS, INC. | 2001-03-20 | — | — | US | disclosed |