Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | C3AR1 | Q16581 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | CCKBR | P32239 | 1/20 | 0.32 |
| ▸ | NPR3 | P17342 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7733653 | 0.86 | MAPT (0.40) | MAPTNPSR1CTSKNQO2 | |
| SCHEMBL7723327 | 0.85 | MAPT (0.44) | MMP1MMP3MMP9MAPTADORA3 | |
| SCHEMBL7730530 | 0.85 | MAPT (0.38) | MMP1MMP3MMP9MAPTADORA3 | |
| SCHEMBL7861048 | 0.78 | C3AR1 (0.44) | SCDMAPTNPSR1CTSKC3AR1 | |
| SCHEMBL7732052 | 0.74 | RAB9A (0.43) | MAPTTDP1 | |
| SCHEMBL7730721 | 0.70 | LTA4H (0.40) | MMP3MAPT | |
| SCHEMBL7731104 | 0.70 | MAPT (0.39) | MMP1MMP3MMP9MAPTADORA3 | |
| SCHEMBL7731051 | 0.70 | LMNA (0.39) | MMP1MMP3MMP9MAPTADORA3 | |
| SCHEMBL7723247 | 0.69 | MAPT (0.38) | MMP1MMP3MMP9MAPTNPSR1 | |
| SCHEMBL7731132 | 0.69 | HDAC4 (0.43) | SCDMMP1MMP3MMP9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436980-B1 | TRANSPORT PROTEIN SUPPRESSORS; MICROBIOCIDES | ESSENTIAL THERAPEUTICS, INC. | 2002-08-20 | — | — | US | disclosed |
| US-6204279-B1 | SECONDARY AMIDE CONTAINING BENZOXAZOLE DERIVATIVES | MICROCIDE PHARMACEUTICALS, INC. | 2001-03-20 | — | — | US | disclosed |