Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | NAAA | Q02083 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MPO | P05164 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1797745 | 0.90 | CA1 (0.68) | CA1CA9NAAAKDM4EMAPT | |
| Phosphoric Acid SCHEMBL8161708 | 0.82 | NAAA (0.60) | CA1CA9NAAAKDM4EMAPT | |
| SCHEMBL8346284 | 0.82 | CA1 (0.59) | CA1CA9NAAAKDM4EMAPT | |
| Isobutyramide SCHEMBL7723757 | 0.79 | CA1 (0.56) | CA1CA9NAAAKDM4EMAPT | |
| SCHEMBL31483721 | 0.78 | HTT (0.64) | CA1CA9NAAAKMT2AHPGD | |
| SCHEMBL26417076 | 0.78 | HTT (0.64) | CA1CA9NAAAKMT2AHPGD | |
| SCHEMBL9132045 | 0.78 | ALOX5 (0.66) | CA1CA9NAAAKDM4EMAPT | |
| SCHEMBL12562532 | 0.76 | NAAA (0.57) | CA1CA9NAAAKDM4EMAPT | |
| SCHEMBL1238119 | 0.76 | NAAA (0.76) | CA1CA9NAAAKDM4EMAPT | |
| SCHEMBL8347809 | 0.76 | CA1 (0.52) | CA1CA9NAAAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1226104-A1 | PHENOXY CARBOXYLIC ACID COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | Emisphere Technologies, Inc. (US) | 2002-07-31 | — | — | EP | disclosed |
| WO-2001032596-A1 | PHENOXY CARBOXYLIC ACID COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 2001-05-10 | — | — | WO | disclosed |