Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.57 |
| ▸ | CCR3 | P51677 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | CARM1 | Q86X55 | 3/20 | 0.51 |
| ▸ | PRMT6 | Q96LA8 | 3/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14389062 | 0.92 | ACHE (0.68) | ACHESIGMAR1CCR3SLC6A3CARM1 | |
| SCHEMBL242759 | 0.85 | ACHE (0.69) | ACHESIGMAR1BCHEBACE1 | |
| SCHEMBL724604 | 0.85 | ACHE (0.69) | ACHESIGMAR1BCHEBACE1 | |
| SCHEMBL242760 | 0.85 | ACHE (0.69) | ACHESIGMAR1BCHEBACE1 | |
| SCHEMBL7724043 | 0.84 | HTR2A (0.51) | ACHECARM1PRMT6BCHEBACE1 | |
| SCHEMBL7725316 | 0.84 | HTR2A (0.51) | ACHECARM1PRMT6BCHEBACE1 | |
| Bromide SCHEMBL2497824 | 0.84 | ACHE (0.68) | ACHESIGMAR1BCHEBACE1 | |
| SCHEMBL4704260 | 0.83 | CARM1 (0.57) | SIGMAR1CARM1PRMT6ALDH1A1GAA | |
| SCHEMBL4704230 | 0.83 | CARM1 (0.57) | SIGMAR1CARM1PRMT6ALDH1A1GAA | |
| SCHEMBL7725283 | 0.83 | CA12 (0.62) | ACHESIGMAR1CCR3SLC6A3CARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6468998-B1 | ANTAGONIZE SEROTONIN 2 RECEPTORS, SUPPRESS PLATELET AGGREGATION, IMPROVE PERIPHERAL CIRCULATION AND PROMOTE LACHRYMATION | MITSUBISHI PHARMA CORPORATION (JP) | 2002-10-22 | — | — | US | disclosed |
| EP-1125922-A1 | PYRROLIDINE COMPOUNDS AND MEDICINAL UTILIZATION THEREOF | Welfide Corporation (JP) | 2001-08-22 | — | — | EP | disclosed |