Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.58 |
| ▸ | DRD4 | P21917 | 3/20 | 0.50 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.50 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | MC4R | P32245 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7723967 | 1.00 | SIGMAR1 (0.58) | SIGMAR1DRD4LTA4HDPP7CXCR3 | |
| SCHEMBL7723996 | 0.88 | HTR2A (0.50) | SIGMAR1DRD4HTR2ADRD2XIAP | |
| SCHEMBL7723995 | 0.88 | HTR2A (0.50) | SIGMAR1DRD4HTR2ADRD2XIAP | |
| SCHEMBL7723959 | 0.87 | SIGMAR1 (0.57) | SIGMAR1DRD4LTA4HDPP7CXCR3 | |
| SCHEMBL7723956 | 0.87 | SIGMAR1 (0.57) | SIGMAR1DRD4LTA4HDPP7CXCR3 | |
| SCHEMBL7723128 | 0.79 | SIGMAR1 (0.56) | SIGMAR1DRD4LTA4HDPP7CXCR3 | |
| SCHEMBL7723126 | 0.79 | SIGMAR1 (0.56) | SIGMAR1DRD4LTA4HDPP7CXCR3 | |
| SCHEMBL7719939 | 0.78 | SIGMAR1 (0.58) | SIGMAR1DRD4LTA4HDPP7CXCR3 | |
| SCHEMBL7719929 | 0.78 | SIGMAR1 (0.58) | SIGMAR1DRD4LTA4HDPP7CXCR3 | |
| SCHEMBL7719935 | 0.78 | SIGMAR1 (0.58) | SIGMAR1DRD4LTA4HDPP7CXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6468998-B1 | ANTAGONIZE SEROTONIN 2 RECEPTORS, SUPPRESS PLATELET AGGREGATION, IMPROVE PERIPHERAL CIRCULATION AND PROMOTE LACHRYMATION | MITSUBISHI PHARMA CORPORATION (JP) | 2002-10-22 | — | — | US | disclosed |
| EP-1125922-A1 | PYRROLIDINE COMPOUNDS AND MEDICINAL UTILIZATION THEREOF | Welfide Corporation (JP) | 2001-08-22 | — | — | EP | disclosed |