Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 3/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.46 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.44 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7724068 | 1.00 | SIGMAR1 (0.53) | SIGMAR1OPRM1MMELTA4HDRD4 | |
| SCHEMBL7719835 | 0.90 | CCR3 (0.50) | DRD4CACNA1GCCR3HTR2ADRD2 | |
| SCHEMBL7719830 | 0.90 | CCR3 (0.50) | DRD4CACNA1GCCR3HTR2ADRD2 | |
| SCHEMBL7725271 | 0.80 | SIGMAR1 (0.57) | SIGMAR1OPRM1MMELTA4HDRD4 | |
| SCHEMBL7725276 | 0.80 | SIGMAR1 (0.57) | SIGMAR1OPRM1MMELTA4HDRD4 | |
| SCHEMBL7729605 | 0.80 | SIGMAR1 (0.57) | SIGMAR1OPRM1MMELTA4HDRD4 | |
| SCHEMBL7729598 | 0.80 | SIGMAR1 (0.57) | SIGMAR1OPRM1MMELTA4HDRD4 | |
| SCHEMBL7719838 | 0.77 | SIGMAR1 (0.57) | SIGMAR1LTA4HDRD4DPP7CXCR3 | |
| SCHEMBL7719831 | 0.77 | SIGMAR1 (0.57) | SIGMAR1LTA4HDRD4DPP7CXCR3 | |
| SCHEMBL7729574 | 0.76 | HSD11B1 (0.59) | SIGMAR1LTA4HDRD4HTR2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6468998-B1 | ANTAGONIZE SEROTONIN 2 RECEPTORS, SUPPRESS PLATELET AGGREGATION, IMPROVE PERIPHERAL CIRCULATION AND PROMOTE LACHRYMATION | MITSUBISHI PHARMA CORPORATION (JP) | 2002-10-22 | — | — | US | disclosed |