Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CCR5 | P51681 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 3/20 | 0.51 |
| ▸ | DRD4 | P21917 | 3/20 | 0.49 |
| ▸ | CTSK | P43235 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7724060 | 1.00 | KCNA3 (0.59) | KCNA3SIGMAR1KMT2AL3MBTL1CCR5 | |
| SCHEMBL22928915 | 0.94 | KCNA3 (0.66) | KCNA3SIGMAR1KMT2AL3MBTL1CCR5 | |
| SCHEMBL2241423 | 0.89 | KMT2A (0.63) | KCNA3SIGMAR1KMT2AL3MBTL1DRD2 | |
| SCHEMBL178929 | 0.89 | KMT2A (0.63) | KCNA3SIGMAR1KMT2AL3MBTL1DRD2 | |
| SCHEMBL2241424 | 0.89 | KMT2A (0.63) | KCNA3SIGMAR1KMT2AL3MBTL1DRD2 | |
| SCHEMBL7724023 | 0.88 | KCNA3 (0.49) | KCNA3DRD2DRD4CTSK | |
| SCHEMBL7724014 | 0.88 | KCNA3 (0.49) | KCNA3DRD2DRD4CTSK | |
| SCHEMBL1707811 | 0.88 | SIGMAR1 (0.56) | KCNA3SIGMAR1KMT2AL3MBTL1 | |
| SCHEMBL8258415 | 0.88 | KCNA3 (0.54) | KCNA3KMT2AL3MBTL1CCR5LTA4H | |
| SCHEMBL23140715 | 0.87 | KCNA3 (0.48) | KCNA3SIGMAR1KMT2AL3MBTL1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6468998-B1 | ANTAGONIZE SEROTONIN 2 RECEPTORS, SUPPRESS PLATELET AGGREGATION, IMPROVE PERIPHERAL CIRCULATION AND PROMOTE LACHRYMATION | MITSUBISHI PHARMA CORPORATION (JP) | 2002-10-22 | — | — | US | disclosed |
| EP-1125922-A1 | PYRROLIDINE COMPOUNDS AND MEDICINAL UTILIZATION THEREOF | Welfide Corporation (JP) | 2001-08-22 | — | — | EP | disclosed |